一种合成C2-取代咪唑鎓离子液体的简便方法。

A facile route to C2-substituted imidazolium ionic liquids.

作者信息

Ennis Elliot, Handy Scott T

机构信息

Department of Chemistry, Middle Tennessee State University, Murfreesboro, TN 37132, USA.

出版信息

Molecules. 2009 Jun 19;14(6):2235-45. doi: 10.3390/molecules14062235.

DOI:10.3390/molecules14062235

PMID:19553895

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6254211/

Abstract

A convenient route for the preparation of C2-substituted imidazolium ionic liquids is reported. This method involves the alkylation of N-heterocyclic carbenes, which are readily generated from the C2-unsubstituted imidazolium ionic liquids. It works well for non-functionalized alkyl chlorides, and less well for alkyl bromides and iodides, likely due to competing elimination reactions. The resulting C2-substituted salts can be transformed into ionic liquids via standard anion metathesis reactions.

摘要

报道了一种制备C2-取代咪唑鎓离子液体的简便方法。该方法涉及N-杂环卡宾的烷基化反应，N-杂环卡宾可由C2-未取代的咪唑鎓离子液体容易地生成。该方法对非官能化的烷基氯效果良好，而对烷基溴和烷基碘效果较差，这可能是由于竞争消除反应所致。通过标准的阴离子复分解反应，所得的C2-取代盐可转化为离子液体。