Rinker Brian, Vasconez Henry C
Division of Plastic Surgery, University of Kentucky, Lexington, Kentucky, USA.
Can J Plast Surg. 2006 Spring;14(1):41-4. doi: 10.1177/229255030601400104.
The debate as to the pathogenesis of constriction band syndrome began with Hippocrates and continues today. The exogenous theory attributes the condition to entanglement of the fetus in the amniotic remnants following premature rupture of the amnion, which is in contrast to the endogenous, or genetic, mechanism.A case of constriction band syndrome in the setting of in vitro fertilization, where the child was genetically unrelated to the birth mother, is presented. Constriction band syndrome has been reported following amniocentesis and chorionic villus sampling, but it has not heretofore been presented in the setting of in vitro fertilization. In addition, the present case presents an opportunity to separate maternal from genetic factors and, possibly, shed some light on the etiology of the condition.
关于束带综合征发病机制的争论始于希波克拉底时代,一直持续至今。外因理论认为该病症是由于羊膜过早破裂后胎儿被羊膜残余物缠住所致,这与内因或遗传机制形成对比。本文报告了一例体外受精情况下发生的束带综合征病例,该患儿与生母无遗传关系。此前已有关于羊膜穿刺术和绒毛取样术后发生束带综合征的报道,但体外受精情况下尚未有此类病例。此外,本病例为区分母体因素和遗传因素提供了契机,可能有助于阐明该病症的病因。