Rogier C, Henry M-C, Trape J-F
URMITE, UMR6236, Institut de recherche biomédicale des armées, Allée du Médecin colonel Jamot, Parc du Pharo, Marseille cedex, France.
Med Trop (Mars). 2009 Apr;69(2):123-42.
For decades malarial control has been implemented to control the impact of the disease on the health of populations living in endemic zones. The use of artemisinine combination therapy, intermittent preventive treatment for children and pregnant women, vector-control methods such as long-lasting insecticide-impregnated mosquito nets and indoor remanent insecticide spraying has proven to be effective. These practices have lead to such an extensive reduction of the malaria burden in some endemic areas that the objective of eradication that was unimaginable a few years ago is now back to the forefront. Regardless of the method chosen, careful evaluation and surveillance of its effectiveness in man is necessary. Achieving epidemiologic impact is the main goal of malaria control methods. The main measures for evaluation involve parasitological and clinical aspects of human malaria. The purpose of this article is to review methods used for epidemiologic evaluation of malaria burden.
几十年来,人们一直在实施疟疾控制措施,以控制该疾病对流行地区居民健康的影响。青蒿素联合疗法、针对儿童和孕妇的间歇性预防治疗、诸如长效杀虫剂浸渍蚊帐和室内滞留杀虫剂喷洒等病媒控制方法已被证明是有效的。这些措施已使一些流行地区的疟疾负担大幅减轻,以至于几年前还难以想象的根除目标如今又重新成为首要任务。无论选择何种方法,都有必要对其在人体中的有效性进行仔细评估和监测。实现流行病学影响是疟疾控制方法的主要目标。评估的主要措施涉及人类疟疾的寄生虫学和临床方面。本文的目的是综述用于疟疾负担流行病学评估的方法。