[Unstable angina pectoris: outcomes of acute period and determinative factors].

AIM

To follow up for 28 days outcomes of unstable angina (UA) and to determine factors affecting the disease course and negative potential of these factors.

MATERIAL AND METHODS

Basing on UA clinical manifestations, 1477 patients aged 20-70 years observed in Tomsk in 2003-2004 were divided into 4 groups: group 1--patients with angina of new onset; group 2--patients with more frequent angina attacks; group 3--patients with more frequent and more severe angina attacks (longer, more painful, attacks at rest, less effective arrest with nitroglycerin); group 4--20 min and longer anginal attacks).

RESULTS

On the disease day 29 UA stabilization was achieved in 1096 (74.12%) patients, UA exacerbation without acute coronary pathology (acute myocardial infarction or acute coronary insufficiency) was seen in 7 (0.47%) patients, 375 (25.41%) UA patients had acute myocardial infarction. The greatest number of acute coronary episodes (51.3%) occurred in group 1 patients. Myocardial infarction developed least frequently in group 4 patients (3.3%).

CONCLUSION

Clinical symptoms of UA, ECG ischemic changes and diabetes mellitus are factors of UA unfavourable outcome.