Coles Martyn P
Department of Chemistry, University of Sussex, Falmer, Brighton, UKBN1 9QJ, UK.
Chem Commun (Camb). 2009 Jul 7(25):3659-76. doi: 10.1039/b901940e. Epub 2009 May 27.
Bicyclic guanidines have physical, electronic and chemical properties that differentiate them from their acyclic counterparts, with many of these characteristics directly imposed by the rigid framework. These distinctive features have led to this class of molecule finding practical applications in many areas of chemistry, including organocatalysis and as ligands in coordination compounds. In addition to the neutral molecules, the corresponding cationic (guanidinium) and anionic (guanidinate) species have also been widely studied. Applications of these ions range from anion recognition and supramolecular arrays involving guanidinium salts, to the utilization of bicyclic guanidinate anions as ligands for metal compounds and clusters. This article reviews the chemistry of these compounds in light of recent advances in the synthesis of new derivatives, highlighting the potential for cross-stimulation of different areas.
双环胍具有物理、电子和化学性质，使其有别于其开环类似物，其中许多特性直接由刚性骨架决定。这些独特的特征使这类分子在化学的许多领域都有实际应用，包括有机催化以及作为配位化合物中的配体。除了中性分子外，相应的阳离子（胍鎓）和阴离子（胍基化物）物种也得到了广泛研究。这些离子的应用范围从涉及胍盐的阴离子识别和超分子阵列，到利用双环胍基化物阴离子作为金属化合物和簇的配体。本文根据新衍生物合成的最新进展，综述了这些化合物的化学性质，突出了不同领域交叉刺激的潜力。
