BioPhysics Group, Department of Mechanical Engineering, University College London, UK.
J Tissue Eng Regen Med. 2009 Oct;3(7):562-6. doi: 10.1002/term.185.
Bio-electrosprays, pioneered in 2005, have undergone several developmental studies which have seen this technique evolve as a novel direct in vivo tissue engineering and regenerative medicinal strategy. Those studies have been a hallmark for electrosprays; however, in this communication we report our on-going developmental investigations for exploring bio-electrosprays as a potential medical device and diagnostic protocol. The studies reported here demonstrate the ability to directly jet whole human blood without affecting the genetic make-up, which has been interrogated by way of reverse transcription-polymerase chain reaction (RT-PCR) in comparison to controls (p = 0.7337). These studies demonstrate bio-electrosprays as a possible diagnostic protocol.
生物电喷射技术于 2005 年首创,已经进行了多项发展研究,使这项技术发展成为一种新颖的直接体内组织工程和再生医学策略。这些研究一直是电喷射技术的标志;然而,在本通讯中,我们报告了正在进行的开发性研究,以探索生物电喷射技术作为一种潜在的医疗设备和诊断方案。这里报道的研究表明,有能力直接喷射全血而不影响基因构成,这已经通过逆转录聚合酶链反应(RT-PCR)与对照(p = 0.7337)进行了检测。这些研究表明生物电喷射技术可能是一种诊断方案。