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[系统性红斑狼疮伴神经精神症状患者的脑灌注研究]

[Brain perfusion study in patients with systemic lupus erythematosus and neuropsychiatric symptoms].

作者信息

Paniagua-Correa C, Balsa-Bretón M A, Garcerant-Tafur M, Mariana-Monguia A, García-Alonso M P, Penín-González F J, Pey-Illera C

机构信息

Servicio de Medicina Nuclear, Hospital Universitario de Getafe, Getafe, Madrid, España.

出版信息

Rev Esp Med Nucl. 2009 May-Jun;28(3):121-4. doi: 10.1016/s0212-6982(09)71354-0.

Abstract

Neuropsychiatric manifestations in 25% to 70% of patients with systemic lupus erythematosus (SLE), generally in young people. The variability in its clinical expression and lack of diagnostic methods have hindered the diagnosis of Central Nervous System Lupus. When the literature was reviewed on this subject, an important variability was found between the Single Photon Emission Computed Tomography (SPECT) findings and the patient's clinical symptoms and disease course. The case we are presenting shows the usefulness of brain perfusion SPECT because it shows alterations in the central nervous system that are not detected with other imaging modalities.

摘要

25%至70%的系统性红斑狼疮(SLE)患者会出现神经精神症状,通常发生在年轻人身上。其临床表现的多样性以及缺乏诊断方法阻碍了中枢神经系统狼疮的诊断。在回顾关于这个主题的文献时,发现单光子发射计算机断层扫描(SPECT)结果与患者的临床症状和病程之间存在重要差异。我们呈现的这个病例显示了脑灌注SPECT的有用性,因为它显示了中枢神经系统的改变,而这些改变是其他成像方式无法检测到的。

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