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根据皮提耶尔-萨尔佩特里埃医院的经验制定的成人成釉细胞瘤治疗方案。

A treatment algorithm for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience.

作者信息

Escande Catherine, Chaine André, Menard Philippe, Ernenwein Didier, Ghoul Sonia, Bouattour Ayman, Berdal Ariane, Bertrand Jacques-Charles, Ruhin-Poncet Blandine

机构信息

Stomatology and Maxillofacial Surgery Department, Pitié-Salpêtrière University Hospital, Assistance Publique des Hôpitaux de Paris, Pierre et Marie Curie-Paris6 University, Paris F-75013, France.

出版信息

J Craniomaxillofac Surg. 2009 Oct;37(7):363-9. doi: 10.1016/j.jcms.2009.05.001. Epub 2009 Jun 25.

Abstract

During a 13-year period (from 1994 to 2007), in the Oral and Maxillofacial Surgery Department of the Pitié-Salpêtrière Hospital, 116 new cases of adult ameloblastomas, were analyzed for treatment composed against radiographic presentation, size, histological type. Follow-up and recurrence were also analyzed. Treatment was surgical consisting of enucleations (82%), segmental mandibulectomy (8.3%) resections (24.7%) 85% of them underwent reconstruction. The follow-up was documented for 97%. More than two recurrences occurred in 21% of the patients after the first enucleation: 66% with a "follicular" histological diagnosis. Lenthly, a therapeutic algorithm is suggested for adult ameloblastomas that underlines the importance of the conservative enucleation treatment as far as possible.

摘要

在13年期间(从1994年至2007年),在皮提耶尔-萨尔佩特里埃医院口腔颌面外科,对116例成人成釉细胞瘤新病例进行了分析,分析内容包括针对影像学表现、大小、组织学类型的治疗方法。还对随访情况和复发情况进行了分析。治疗方式为手术,包括摘除术(82%)、下颌骨节段切除术(8.3%)、切除术(24.7%),其中85%的患者接受了重建手术。97%的患者有随访记录。21%的患者在首次摘除术后出现了两次以上复发:66%的患者组织学诊断为“滤泡型”。最后,针对成人成釉细胞瘤提出了一种治疗算法,强调了尽可能采用保守摘除术治疗的重要性。

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