Department of Pulmonary and Critical Care, Marmara University Hospital, Turkey.
Ann Thorac Med. 2009 Jan;4(1):17-20. doi: 10.4103/1817-1737.44780.
Unplanned extubation is quite common in intensive care unit (ICU) patients receiving mechanical ventilatory support. The present study aimed to investigate the effectiveness of noninvasive positive pressure ventilation (NPPV) in patients with unplanned extubation.
A total of 15 patients (12 male, age: 57 ± 24 years, APACHE II score: 19 ± 7) monitored at the medical ICU during the year 2004 who developed unplanned extubation were included in the study. NPPV was tried in all of them following unplanned extubation. Indications for admission to the ICU were as follows: nine patients with pneumonia, three with status epilepticus, one with gastrointestinal bleeding, one with cardiogenic pulmonary edema and one with diffuse alveolar bleeding.
Eleven of the patients (74%) were at the weaning period at the time of unplanned extubation. Among these 11 patients, NPPV was successful in 10 (91%) and only one (9%) was reintubated due to the failure of NPPV. The remaining four patients (26%) had pneumonia and none of them were at the weaning period at the time of extubation, but their requirement for mechanical ventilation was gradually decreasing. Unfortunately, an NPPV attempt for 6-8 h failed and these patients were reintubated.
Patients with unplanned extubation before the weaning criteria are met should be intubated immediately. On the other hand, when extubation develops during the weaning period, NPPV may be an alternative. The present study was conducted with a small number of patients, and larger studies on the effectiveness of NPPV in unplanned extubation are warranted for firm conclusions.
在接受机械通气支持的重症监护病房(ICU)患者中,计划性拔管较为常见。本研究旨在探讨无创正压通气(NPPV)在计划性拔管患者中的应用效果。
2004 年,我们共纳入了在医学 ICU 监测的 15 例(12 例男性,年龄:57 ± 24 岁,APACHE II 评分:19 ± 7)发生计划性拔管的患者。所有患者在计划性拔管后均尝试使用 NPPV。入住 ICU 的指征如下:9 例肺炎,3 例癫痫持续状态,1 例胃肠道出血,1 例心源性肺水肿,1 例弥漫性肺泡出血。
11 例(74%)患者在计划性拔管时处于脱机过程中。这 11 例患者中,NPPV 成功 10 例(91%),仅 1 例(9%)因 NPPV 失败而重新插管。其余 4 例(26%)患者患有肺炎,且在拔管时均未处于脱机过程中,但他们对机械通气的需求逐渐减少。不幸的是,NPPV 尝试 6-8 小时后失败,这些患者重新插管。
在未达到脱机标准而发生计划性拔管的患者应立即插管。另一方面,当在脱机过程中发生计划性拔管时,NPPV 可能是一种替代方法。本研究纳入的患者数量较少,需要进行更大规模的研究来确定 NPPV 在计划性拔管中的有效性。