Mertes P M, Lambert M, Guéant-Rodriguez R M, Aimone-Gastin I, Mouton-Faivre C, Moneret-Vautrin D A, Guéant J L, Malinovsky J M, Demoly P
Service d'Anesthésie-Réanimation Chirurgicale, CHU de Nancy, Hôpital Central, 29 Avenue de Lattre de Tassigny, Nancy Cedex 54035, France.
Immunol Allergy Clin North Am. 2009 Aug;29(3):429-51. doi: 10.1016/j.iac.2009.04.004.
The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents represent the most frequently involved substances, followed by latex and antibiotics, but every drug or substance used may be involved. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests and specific IgE or basophil activation assays.
麻醉期间免疫介导的过敏反应发生率为万分之一至二万分之一。神经肌肉阻滞剂是最常涉及的物质，其次是乳胶和抗生素，但使用的每种药物或物质都可能涉及。诊断依赖于反应时的类胰蛋白酶测量、皮肤试验以及特异性IgE或嗜碱性粒细胞活化试验。
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