Koornstra G, Exalto N
Spaarne Ziekenhuis, afd. Verloskunde en Gynaecologie, Haarlem.
Ned Tijdschr Geneeskd. 1991 Nov 23;135(47):2231-5.
Clinical and ultrasound data of 403 first-trimester pregnancies were collected prospectively. Consequences for determination of gestational age as well as the risk of spontaneous abortion were investigated. There was a clear relation between embryonal growth delay and the risk of spontaneous abortion: the risk of spontaneous abortion was significantly higher if the crown-rump length lagged 7 or more days behind the expected gestation time based on the duration of the amenorrhoea (16% versus 5.0%; p less than 0.01). It is important to know the exact duration of pregnancy, because a difference of one or two weeks can be critical in terms of survival or disability. 22.7% of the pregnant women who had a regular menstrual cycle before this pregnancy appeared to have an embryonal growth delay of seven days or more in relation to the reference curve. This illustrates the necessity of crown-rump length measurements in order to obtain accurate assessment of gestational age, which is fundamental in obstetric care.
前瞻性收集了403例孕早期妊娠的临床和超声数据。研究了对确定孕周的影响以及自然流产风险。胚胎生长延迟与自然流产风险之间存在明显关联：如果根据闭经时间计算的头臀长度比预期孕周落后7天或更多天，则自然流产风险显著更高（16%对5.0%；p<0.01）。了解确切的孕周很重要，因为一两周的差异在生存或残疾方面可能至关重要。在本次妊娠前月经周期规律的孕妇中，22.7%的人相对于参考曲线出现了7天或更长时间的胚胎生长延迟。这说明了进行头臀长度测量以准确评估孕周的必要性，而孕周评估在产科护理中至关重要。
