Kjeldsberg C R, Eyre H J, Totzke H
Blood. 1977 Sep;50(3):493-504.
Evidence for intracellular formation of amyloid fibrils in a patient with kappa light-chain myeloma is described. Amyloid fibrils were seen as intracytoplasmic inclusions within plasma cells, histiocytes, renal tubule cells, and possibly in hepatocytes. Extracellular amyloid was also present. The electron microscopic studies suggest that amyloid fibrils may form in the Golgi apparatus and within lysosomes.
描述了一名κ轻链骨髓瘤患者细胞内形成淀粉样纤维的证据。淀粉样纤维可见于浆细胞、组织细胞、肾小管细胞内的胞质内含物中，也可能见于肝细胞内。也存在细胞外淀粉样物质。电子显微镜研究表明，淀粉样纤维可能在高尔基体和溶酶体内形成。
