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对于伴有固有括约肌缺陷的压力性尿失禁,应选择哪种类型的中段尿道吊带手术进行治疗?无张力阴道吊带术还是经闭孔吊带术。

Which type of mid-urethral sling procedure should be chosen for treatment of stress urinary incontinance with intrinsic sphincter deficiency? Tension-free vaginal tape or transobturator tape.

作者信息

Gungorduk Kemal, Celebi Ibrahim, Ark Cemal, Celikkol Ozgu, Yildirim Gokhan

机构信息

Department of Obstetrics and Gynecology, Istanbul Bakirkoy Women and Childrens' Hospital, Istanbul, Turkey.

出版信息

Acta Obstet Gynecol Scand. 2009;88(8):920-6. doi: 10.1080/00016340903100354.

DOI:10.1080/00016340903100354
PMID:19565366
Abstract

OBJECTIVE

To compare tension-free vaginal tape (TVT) and transobturator tape (TOT) for surgical treatment of stress urinary incontinence (SUI) with intrinsic sphincter deficiency.

DESIGN

Retrospective study.

SETTING

Gynecology department, Bakirkoy Women and Childrens' Hospital, Istanbul.

SAMPLE

Three hundred women urodynamically diagnosed with stress incontinence with intrinsic sphincter deficiency underwent synthetic mid-urethral sling procedures (TVT = 180, TOT = 120).

METHODS

Before the operation, a complete medical history was taken and a gynecologic examination was performed. Subjects with detrusor overactivity or previous sling surgery were excluded. Clinical checkups were conducted at 3, 6, and 12 months, and then annually.

MAIN OUTCOME MEASURES

Intraoperative complications, postoperative complications, and subjective cure rates.

RESULTS

There were no significant differences in demographics between the TVT and TOT groups: mean age, parity, body mass index, menopausal status, and hormone replacement therapy. At a mean follow-up of 31.2 +/- 9.1 (range 12-46) months, the overall cure rates were 78.3% for TVT and 52.5% TOT (p < 0.0001). The risk of treatment failure in women who received TOT was 4.9 times higher than in women who underwent TVT. There were no significant differences in perioperative and postoperative complication rates between the two groups.

CONCLUSION

TVT appears to be the preferable surgical option for the treatment of SUI with intrinsic sphincter deficiency.

摘要

目的

比较无张力阴道吊带术(TVT)和经闭孔尿道中段吊带术(TOT)治疗伴有固有括约肌缺陷的压力性尿失禁(SUI)的效果。

设计

回顾性研究。

地点

伊斯坦布尔巴基尔柯伊妇女儿童医院妇科。

样本

300例经尿动力学诊断为伴有固有括约肌缺陷的压力性尿失禁的女性接受了合成材料尿道中段吊带手术(TVT组180例,TOT组120例)。

方法

术前采集完整病史并进行妇科检查。排除逼尿肌过度活动或既往有吊带手术史的受试者。在3个月、6个月和12个月时进行临床检查,之后每年检查一次。

主要观察指标

术中并发症、术后并发症及主观治愈率。

结果

TVT组和TOT组在人口统计学特征方面无显著差异:平均年龄、产次、体重指数、绝经状态及激素替代治疗情况。平均随访31.2±9.1(范围12 - 46)个月时,TVT组的总体治愈率为78.3%,TOT组为52.5%(p < 0.0001)。接受TOT治疗的女性治疗失败风险比接受TVT治疗的女性高4.9倍。两组围手术期和术后并发症发生率无显著差异。

结论

对于治疗伴有固有括约肌缺陷的SUI,TVT似乎是更可取的手术选择。

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