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用于光学相干断层扫描的傅里叶域锁模激光器的最新进展:1310纳米与1550纳米波长下的成像

Recent developments in Fourier domain mode locked lasers for optical coherence tomography: imaging at 1310 nm vs. 1550 nm wavelength.

作者信息

Biedermann Benjamin R, Wieser Wolfgang, Eigenwillig Christoph M, Huber Robert

机构信息

Lehrstuhl für BioMolekulare Optik, Fakultät für Physik, Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538 Munich, Germany.

出版信息

J Biophotonics. 2009 Jul;2(6-7):357-63. doi: 10.1002/jbio.200910028.

Abstract

We report on recent progress in Fourier domain mode-locking (FDML) technology. The paper focuses on developments beyond pushing the speed of these laser sources. After an overview of improvements to FDML over the last three years, a brief analysis of OCT imaging using FDML lasers with different wavelengths is presented. For the first time, high speed, high quality FDML imaging at 1550 nm is presented and compared to a system at 1310 nm. The imaging results of human skin for both wavelengths are compared and analyzed. Sample arm optics, power on the sample, heterodyne gain, detection bandwidth, colour cut levels and sample location have been identical to identify the influence of difference in scattering and water absorption. The imaging performance at 1310 nm in human skin is only slightly better and the results suggest that water absorption only marginally affects the penetration depth in human skin at 1550 nm. For several applications this wavelength may be preferred.

摘要

我们报告了傅里叶域锁模(FDML)技术的最新进展。本文重点关注超越提高这些激光源速度的发展情况。在概述过去三年FDML的改进之后,对使用不同波长的FDML激光器进行的光学相干断层扫描(OCT)成像进行了简要分析。首次展示了1550纳米处的高速、高质量FDML成像,并与1310纳米处的系统进行了比较。对两种波长下人体皮肤的成像结果进行了比较和分析。样本臂光学器件、样本上的功率、外差增益、检测带宽、颜色截止水平和样本位置均保持一致,以确定散射和吸水差异的影响。1310纳米在人体皮肤中的成像性能仅略好一些,结果表明吸水对1550纳米在人体皮肤中的穿透深度影响很小。对于几种应用来说,这个波长可能更受青睐。

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