Ootaki Yoshio, Ootaki Chiyo, Massiello Alex, Horvath David, Chen Ji-Feng, Mihaljevic Tomislav, Navia Jose L, Smedira Nicholas G, Golding Leonard A R, Fukamachi Kiyotaka
Department of Thoracic and Cardiovascular Surgery, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Artif Organs. 2009 Jul;33(7):558-61. doi: 10.1111/j.1525-1594.2009.00741.x.
The DexAide right ventricular assist device (RVAD) has been developed as an implantable RVAD. The purpose of this study was to determine the final design and optimal anatomical placement of the DexAide RVAD when implanted simultaneously with either of two commercially available left ventricular assist devices (LVADs) in patients. A mock-up DexAide RVAD was used to assess configuration with each of two types of commercially available LVADs at the time of LVAD implantation in three human clinical cases. The pump body of the DexAide RVAD was placed either in the preperitoneal space or in the right thoracic cavity. The DexAide RVAD placed into the right thoracic cavity is suitable for use with the Novacor or HeartMate II LVADs. The results of this study will guide the finalization of the inflow cannula and optimal placement of the DexAide RVAD for human clinical trials.
德赛德右心室辅助装置（RVAD）已被开发为一种可植入式RVAD。本研究的目的是确定在患者中与两种市售左心室辅助装置（LVAD）之一同时植入时，德赛德RVAD的最终设计和最佳解剖位置。在三例人类临床病例中，在植入LVAD时，使用德赛德RVAD模型评估其与两种市售LVAD的配置情况。德赛德RVAD的泵体放置在腹膜前间隙或右胸腔内。放置在右胸腔内的德赛德RVAD适用于与诺瓦科尔或HeartMate II LVAD一起使用。本研究结果将指导流入插管的最终确定以及德赛德RVAD在人体临床试验中的最佳放置位置。
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