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万古霉素治疗指南:美国传染病学会、美国卫生系统药师协会和传染病药师协会共识推荐摘要

Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists.

作者信息

Rybak Michael J, Lomaestro Ben M, Rotschafer John C, Moellering Robert C, Craig Willam A, Billeter Marianne, Dalovisio Joseph R, Levine Donald P

机构信息

Anti-Infective Research Laboratory, Department of Pharmacy Practice, College of Pharmacy & Health Sciences, Wayne State University, Detroit Receiving Hospital & University Health Center, Detroit, Michigan 48201, USA.

出版信息

Clin Infect Dis. 2009 Aug 1;49(3):325-7. doi: 10.1086/600877.

Abstract

Practice guidelines for therapeutic monitoring of vancomycin treatment for Staphylococcus aureus infection in adult patients were reviewed by an expert panel of the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists. A literature review of existing evidence regarding vancomycin dosing and monitoring of serum concentrations, in addition to patient outcomes combined with expert opinion regarding the drug's pharmacokinetic, pharmacodynamic, and safety record, resulted in new recommendations for targeting and adjustment of vancomycin therapy.

摘要

美国传染病学会、美国卫生系统药师协会和传染病药师协会的一个专家小组对成人金黄色葡萄球菌感染万古霉素治疗的治疗监测实践指南进行了审查。除了患者预后外,对现有关于万古霉素给药和血清浓度监测的证据进行文献综述,并结合关于该药物药代动力学、药效学和安全记录的专家意见,得出了万古霉素治疗靶向和调整的新建议。

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