• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

万古霉素治疗指南：美国传染病学会、美国卫生系统药师协会和传染病药师协会共识推荐摘要

Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists.

作者信息

Rybak Michael J, Lomaestro Ben M, Rotschafer John C, Moellering Robert C, Craig Willam A, Billeter Marianne, Dalovisio Joseph R, Levine Donald P

机构信息

Anti-Infective Research Laboratory, Department of Pharmacy Practice, College of Pharmacy & Health Sciences, Wayne State University, Detroit Receiving Hospital & University Health Center, Detroit, Michigan 48201, USA.

出版信息

Clin Infect Dis. 2009 Aug 1;49(3):325-7. doi: 10.1086/600877.

DOI:10.1086/600877
PMID:19569969
Abstract

Practice guidelines for therapeutic monitoring of vancomycin treatment for Staphylococcus aureus infection in adult patients were reviewed by an expert panel of the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists. A literature review of existing evidence regarding vancomycin dosing and monitoring of serum concentrations, in addition to patient outcomes combined with expert opinion regarding the drug's pharmacokinetic, pharmacodynamic, and safety record, resulted in new recommendations for targeting and adjustment of vancomycin therapy.

摘要

美国传染病学会、美国卫生系统药师协会和传染病药师协会的一个专家小组对成人金黄色葡萄球菌感染万古霉素治疗的治疗监测实践指南进行了审查。除了患者预后外，对现有关于万古霉素给药和血清浓度监测的证据进行文献综述，并结合关于该药物药代动力学、药效学和安全记录的专家意见，得出了万古霉素治疗靶向和调整的新建议。

相似文献

1
Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists.万古霉素治疗指南：美国传染病学会、美国卫生系统药师协会和传染病药师协会共识推荐摘要
Clin Infect Dis. 2009 Aug 1;49(3):325-7. doi: 10.1086/600877.
2
Therapeutic monitoring of vancomycin in adults summary of consensus recommendations from the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists.成人万古霉素治疗药物监测：美国卫生系统药剂师学会、美国感染病学会和感染病学会药剂师协会共识推荐总结。
Pharmacotherapy. 2009 Nov;29(11):1275-9. doi: 10.1592/phco.29.11.1275.
3
Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.执行摘要：针对耐甲氧西林金黄色葡萄球菌严重感染的万古霉素治疗监测：美国卫生系统药师协会、美国传染病学会、儿科传染病学会及传染病药师学会的修订共识指南与综述
Pharmacotherapy. 2020 Apr;40(4):363-367. doi: 10.1002/phar.2376. Epub 2020 Mar 29.
4
Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.针对耐甲氧西林金黄色葡萄球菌严重感染的万古霉素治疗监测：美国卫生系统药师协会、美国传染病学会、儿科传染病学会及传染病药师学会的修订共识指南及综述
Am J Health Syst Pharm. 2020 May 19;77(11):835-864. doi: 10.1093/ajhp/zxaa036.
5
Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists.成人患者万古霉素的治疗监测：美国卫生系统药师协会、美国传染病学会和传染病药师协会的共识综述
Am J Health Syst Pharm. 2009 Jan 1;66(1):82-98. doi: 10.2146/ajhp080434.
6
Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.针对耐甲氧西林金黄色葡萄球菌严重感染的万古霉素治疗监测：美国卫生系统药师协会、美国传染病学会、儿科传染病学会及传染病药师学会修订的共识指南及综述
Clin Infect Dis. 2020 Sep 12;71(6):1361-1364. doi: 10.1093/cid/ciaa303.
7
Vancomycin dosing in critically ill trauma patients: The VANCTIC Study.严重创伤患者万古霉素的剂量：VANCTIC 研究。
J Trauma Acute Care Surg. 2019 Nov;87(5):1164-1171. doi: 10.1097/TA.0000000000002492.
8
Balancing vancomycin efficacy and nephrotoxicity: should we be aiming for trough or AUC/MIC?平衡万古霉素的疗效与肾毒性：我们应该以谷浓度还是AUC/MIC为目标？
Paediatr Drugs. 2015 Apr;17(2):97-103. doi: 10.1007/s40272-015-0117-5.
9
Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.执行摘要：针对耐甲氧西林金黄色葡萄球菌严重感染的万古霉素治疗监测：美国卫生系统药师协会、美国传染病学会、儿科传染病学会和传染病药师协会的修订共识指南及综述
J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):281-284. doi: 10.1093/jpids/piaa057.
10
Monitoring of vancomycin serum levels for the treatment of staphylococcal infections.监测万古霉素血清水平以治疗葡萄球菌感染。
Clin Microbiol Infect. 2006 Jan;12(1):92-5. doi: 10.1111/j.1469-0691.2005.01306.x.

引用本文的文献

1
In Vivo Antibiotic Elution and Inflammatory Response During Two-Stage Total Knee Arthroplasty Revision: A Microdialysis Pilot Study.两阶段全膝关节置换翻修术中的体内抗生素洗脱及炎症反应：一项微透析初步研究
Antibiotics (Basel). 2025 Jul 24;14(8):742. doi: 10.3390/antibiotics14080742.
2
Impact of Extracorporeal Membrane Oxygenation Life Support on Vancomycin Population Pharmacokinetics in Critical Illness: A Systematic Review.体外膜肺氧合生命支持对危重症患者万古霉素群体药代动力学的影响：一项系统评价
Clin Drug Investig. 2025 Aug 7. doi: 10.1007/s40261-025-01449-4.
3
A real-world study of the optimal cut-off value for vancomycin trough concentration associated with outcomes in children infected with drug-resistant Gram-positive bacteria.
一项关于万古霉素谷浓度最佳临界值与耐革兰氏阳性菌感染儿童预后相关性的真实世界研究。
Front Pediatr. 2025 Jul 21;13:1597306. doi: 10.3389/fped.2025.1597306. eCollection 2025.
4
Pharmacotherapy variability and precision medicine in neurocritical care.神经重症监护中的药物治疗变异性与精准医学
Front Neurol. 2025 Jul 18;16:1630163. doi: 10.3389/fneur.2025.1630163. eCollection 2025.
5
A Large Cohort Study to Identify Risk Factors of Acute Kidney Injury in Pediatric Patients Undergoing Intravenous Vancomycin Therapy.一项大型队列研究，旨在确定接受静脉万古霉素治疗的儿科患者急性肾损伤的危险因素。
Pharmacotherapy. 2025 Aug;45(8):504-511. doi: 10.1002/phar.70044. Epub 2025 Jul 26.
6
A Multicenter Randomized Controlled Study on Pharmacokinetic-Guided Vancomycin Use in Children With Severe Infections.一项关于药代动力学指导下万古霉素用于重症感染儿童的多中心随机对照研究。
Clin Transl Sci. 2025 Aug;18(8):e70309. doi: 10.1111/cts.70309.
7
Machine learning approach for personalized vancomycin steady-state trough concentration prediction: a superior approach over Bayesian population pharmacokinetic model.用于个性化万古霉素稳态谷浓度预测的机器学习方法：一种优于贝叶斯群体药代动力学模型的方法。
Front Pharmacol. 2025 Jun 12;16:1549500. doi: 10.3389/fphar.2025.1549500. eCollection 2025.
8
Identification of risk factors for supra-therapeutic vancomycin trough levels in ventilator-assisted critical care patients based on integrated modeling and multi-criteria decision analysis.基于综合建模和多标准决策分析确定机械通气重症监护患者万古霉素谷浓度高于治疗水平的危险因素
PLoS One. 2025 May 23;20(5):e0324510. doi: 10.1371/journal.pone.0324510. eCollection 2025.
9
Evaluating the clinical impact of targeting lower versus higher serum vancomycin trough: a retrospective study using a desirability of outcome ranking (DOOR) analysis.评估较低与较高血清万古霉素谷浓度靶向治疗的临床影响：一项使用结局期望排名（DOOR）分析的回顾性研究。
Eur J Clin Microbiol Infect Dis. 2025 May 15. doi: 10.1007/s10096-025-05161-1.
10
Effects of AUC-Based Vancomycin Therapeutic Drug Monitoring on AKI Incidence and Drug Utilization: A Propensity Score-Weighted Analysis.基于曲线下面积的万古霉素治疗药物监测对急性肾损伤发生率和药物使用的影响：一项倾向评分加权分析。
J Clin Med. 2025 Mar 10;14(6):1863. doi: 10.3390/jcm14061863.