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既往心肌梗死患者室性心动过速消融的接触式与非接触式标测

Contact versus noncontact mapping for ablation of ventricular tachycardia in patients with previous myocardial infarction.

作者信息

Pratola Claudio, Baldo Elisa, Toselli Tiziano, Notarstefano Pasquale, Artale Paolo, Ferrari Roberto

机构信息

Chair of Cardiology, S. Anna University Hospital, Ferrara, Italy.

出版信息

Pacing Clin Electrophysiol. 2009 Jul;32(7):842-50. doi: 10.1111/j.1540-8159.2009.02398.x.

Abstract

INTRODUCTION

The aim of this study was to compare contact versus noncontact mapping for radiofrequency (RF) ablation of any sustained post-myocardial infarction (MI) ventricular tachycardia (VT).

METHODS

Forty patients with tolerated VT post-MI were randomized to RF ablation with contact (group 1) or noncontact (group 2) mapping systems. In both groups ablation of tolerated VT was guided by VT activation map confirmed by concealed entrainment. When untolerated VTs were induced, ablation was performed in group 1 according to pace mapping starting from the scar border zone and in group 2 according to the VT activation map confirmed by pace mapping.

RESULTS

No differences were seen between the groups in terms of acute success rate of clinical VT ablation (95% vs 100%, respectively; P = ns) and in the noninducibility of any VT at the end of the procedure (55% vs 85%, respectively; P = 0.08). Moreover, untolerated VTs were eliminated in 30% of group 1 versus 83.3% of group 2 patients (P < 0.05). The mean total procedural and fluoroscopy times were 236.4 +/- 42.7 and 29.0 +/- 7.8 minutes in group 1 and 144.5 +/- 50.8 and 23.4 +/- 5.8 minutes in group 2 (P < 0.001 and < 0.05, respectively). At a mean follow-up of 15.2 +/- 6.7 months no differences were seen in VT recurrences between groups, but noninducibility at the end of the procedure was predictive of freedom from recurrences (P < 0.001).

CONCLUSION

Both systems are useful for ablation of tolerated VT. Noncontact mapping is more effective for ablation of untolerated VT and allows the reduction of procedural and fluoroscopy times. Noninducibility at the end of the procedure seems predictive of freedom from recurrences during follow-up.

摘要

引言

本研究旨在比较接触式标测与非接触式标测在射频(RF)消融任何持续性心肌梗死后(MI)室性心动过速(VT)中的应用。

方法

40例心肌梗死后可耐受室性心动过速的患者被随机分为使用接触式标测系统(第1组)或非接触式标测系统(第2组)进行射频消融。两组中,可耐受室性心动过速的消融均由隐匿性拖带证实的室性心动过速激动标测引导。当诱发出不可耐受的室性心动过速时,第1组根据从瘢痕边界区开始的起搏标测进行消融,第2组根据起搏标测证实的室性心动过速激动标测进行消融。

结果

两组在临床室性心动过速消融的急性成功率方面(分别为95%和100%;P=无统计学意义)以及手术结束时任何室性心动过速的不可诱发性方面(分别为55%和85%;P=0.08)均无差异。此外,第1组30%的患者与第2组83.3%的患者不可耐受的室性心动过速被消除(P<0.05)。第1组的平均总手术时间和透视时间分别为236.4±42.7分钟和29.0±7.8分钟,第2组分别为144.5±50.8分钟和23.4±5.8分钟(分别为P<0.001和<0.05)。平均随访15.2±6.7个月时,两组间室性心动过速复发情况无差异,但手术结束时的不可诱发性可预测无复发(P<0.001)。

结论

两种系统对于可耐受室性心动过速的消融均有用。非接触式标测对于不可耐受室性心动过速的消融更有效,并可减少手术时间和透视时间。手术结束时的不可诱发性似乎可预测随访期间无复发。

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