University Heart Centre Bochum, BG Clinic Bergmannsheil, Ruhr-Universität Bochum, Bochum, Germany.
Am J Cardiol. 2010 May 1;105(9):1235-9. doi: 10.1016/j.amjcard.2009.12.038. Epub 2010 Mar 11.
The ablation of ventricular tachycardia (VT) can be achieved using anatomically guided approaches using differentiated mapping and ablation techniques. The aim of this study was to evaluate the efficacy of limited linear ablation in the VT exit region identified during sinus rhythm mapping alone. One hundred fifteen consecutive patients presenting for ablation of post-myocardial infarction VT were included. After induction of the target VT during invasive electrophysiology, left ventricular substrate mapping during sinus rhythm to identify scar and border zone on the basis of endocardial bipolar voltage was performed. The exit site of the target VT was regionalized by a simplified vector pace mapping approach and targeted using limited linear ablation within the scar border zone. Seventy-seven percent of all inducible VT was successfully ablated. In 71 patients (62%), no sustained VT was inducible at the end of ablation procedure (complete success). During a median follow-up period of 16 + or - 10 months, 89 patients (77%) had no documented sustained ventricular arrhythmia. Seven patients (2%) had recurrences of the initially ablated VT, and 16 (14%) had new-onset VT. Patients with complete success had a significantly lower number of ventricular arrhythmia reoccurrences than patients with incomplete ablation success (11% vs 37%, p = 0.002). In conclusion, postinfarct VT was effectively ablated in 97% of patients without mapping during ongoing VT using a simplified regional linear ablation approach targeting the scar border zone. Freedom from any ventricular arrhythmia was achieved in 77% of patients during midterm follow-up.
室性心动过速(VT)的消融可以通过解剖学引导的方法,使用差异化的标测和消融技术来实现。本研究的目的是评估在窦性心律标测期间单独识别的 VT 出口区域进行有限线性消融的疗效。连续纳入 115 例因心肌梗死后 VT 消融的患者。在侵入性电生理检查中诱发目标 VT 后,进行窦性心律下的左心室基质标测,根据心内膜双极电压识别瘢痕和边界区。目标 VT 的出口部位通过简化的向量起搏标测方法进行分区,并在瘢痕边界区内进行有限线性消融。所有可诱发的 VT 中,77%的患者可成功消融。在 71 例患者(62%)中,消融结束时无持续性 VT 可诱发(完全成功)。在中位随访 16+/-10 个月期间,89 例患者(77%)无持续性室性心律失常记录。7 例患者(2%)最初消融的 VT 复发,16 例患者(14%)新发 VT。完全成功的患者与不完全消融成功的患者相比,心律失常复发的次数明显减少(11% vs 37%,p=0.002)。总之,97%的患者在无持续 VT 时使用简化的区域性线性消融方法靶向瘢痕边界区进行消融,可有效消融梗死区 VT。在中期随访中,77%的患者无任何室性心律失常。