Jennings William C, Turman Martin A, Taubman Kevin E
Department of Surgery, University of Oklahoma College of Medicine, Tulsa, OK 74135, USA.
J Pediatr Surg. 2009 Jul;44(7):1377-81. doi: 10.1016/j.jpedsurg.2008.11.001.
Hemodialysis (HD) for children and adolescents with renal failure is increasingly common in the United States. Consensus opinion views an arteriovenous fistula (AVF) as the best long-term access option, although catheter-based HD remains the most common vascular access in children and has greater risks of complications and higher mortality rates than AVF access. This report reviews our experience with children and adolescents undergoing vascular access operations.
We reviewed 721 consecutive vascular access patients who had vascular access surgery by a single surgeon during the previous 5 years. Ten patients 20 years or younger were included in this study. In addition to physical examination, each patient had preoperative vascular ultrasound mapping by the operating surgeon. A radiocephalic AVF (RC-AVF) at the wrist was the first choice for dialysis access when feasible; however, the patients in this report were generally seen after years of intravenous access and venipunctures that necessitated more proximal AVF constructions. A proximal radial artery AVF (PRA-AVF) was our most common choice for vascular access when an RC-AVF was not suitable.
Patient ages were 9 to 20 years (mean, 16). Seven were male. Renal failure was caused by glomerulnephitis in 4 patients, 3 had a history of obstuctive uropathy, 2 were diabetic and one had congenital nephrotic syndrome. Eight patients had PRA-AVFs created, 1 had an RC-AVF, and 1 patient required a transposition AVF. Follow-up was 4 to 56 months (mean, 32 months). Primary, primary-assisted, and cumulative patencies were 77.8%, 100%, and 100% at 24 months. No prosthetic grafts were used in any vascular access patient during the study period.
We found HD access in children and adolescents was reliably established through use of a PRA-AVF when an RC-AVF was not feasible. Access sites were often possible through the upper arm cephalic veins and/or with retrograde flow into the forearm. Cumulative (secondary) patency was 100% at 24 months.
在美国,为患有肾衰竭的儿童和青少年进行血液透析(HD)越来越普遍。尽管基于导管的血液透析仍是儿童中最常见的血管通路,且与动静脉内瘘(AVF)通路相比并发症风险更高、死亡率更高,但共识意见认为动静脉内瘘是最佳的长期通路选择。本报告回顾了我们在儿童和青少年接受血管通路手术方面的经验。
我们回顾了在过去5年中由一位外科医生连续进行血管通路手术的721例血管通路患者。本研究纳入了10名20岁及以下的患者。除体格检查外,每位患者术前均由手术医生进行血管超声定位。在可行的情况下,腕部的头静脉桡动脉内瘘(RC-AVF)是透析通路的首选;然而,本报告中的患者通常是在经过多年静脉通路和静脉穿刺后才就诊,这使得需要构建更靠近近端的动静脉内瘘。当头静脉桡动脉内瘘不合适时,近端桡动脉动静脉内瘘(PRA-AVF)是我们最常用的血管通路选择。
患者年龄为9至20岁(平均16岁)。7例为男性。4例患者的肾衰竭由肾小球肾炎引起,3例有梗阻性尿路病病史,2例为糖尿病患者,1例患有先天性肾病综合征。8例患者创建了近端桡动脉动静脉内瘘,1例为头静脉桡动脉内瘘,1例患者需要进行转位动静脉内瘘。随访时间为4至56个月(平均32个月)。24个月时的初次通畅率、初次辅助通畅率和累积通畅率分别为77.8%、100%和100%。在研究期间,所有血管通路患者均未使用人工血管移植物。
我们发现,当头静脉桡动脉内瘘不可行时,通过使用近端桡动脉动静脉内瘘可为儿童和青少年可靠地建立血液透析通路。通常可以通过上臂头静脉和/或逆向流入前臂来建立通路部位。24个月时的累积(二次)通畅率为100%。