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经口肠内营养与空肠造瘘肠内营养在急性腐蚀性损伤中的对比评价:回顾性分析。

Comparative evaluation of nasoenteral feeding and jejunostomy feeding in acute corrosive injury: a retrospective analysis.

机构信息

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Gastrointest Endosc. 2009 Nov;70(5):874-80. doi: 10.1016/j.gie.2009.03.009. Epub 2009 Jul 1.

Abstract

BACKGROUND

Nutritional support in corrosive injury patients is traditionally achieved through total parenteral nutrition (TPN) or jejunostomy feeding (JF). There are no reports of nasoenteral tube feeding in patients with corrosive ingestion.

OBJECTIVE

We report our experience with nasoenteral tube feeding (NETF) and compare the outcome of these patients with those undergoing JF.

SETTING

Tertiary medical center in North India.

DESIGN AND INTERVENTION

The records of 53 and 43 patients with severe acute corrosive injury who underwent NETF and JF, respectively, were reviewed. All had received a 50-kcal/kg, 2-g/kg protein homogenized liquid diet for 8 weeks. A contrast study was performed at 8 weeks, and body weight and serum albumin levels were recorded at hospitalization and at 8 weeks.

MAIN OUTCOME MEASUREMENTS

Change in weight and serum albumin at 8 weeks and stricture development rate.

RESULTS

Strictures developed in 41 (80.39%) and 36 (83.72%) patients in the NETF and JF groups, respectively. Development of esophageal stricture (P = .71) and gastric stenosis (P = .89) was comparable in the 2 groups. No significant changes in serum albumin and weight were noted at 8 weeks in either group. The complication rate was lower in the NETF group compared with the JF group. Although all of the patients in the NETF group had a patent lumen, 5 in the JF group had total obstruction precluding endoscopic intervention.

LIMITATIONS

Retrospective study design.

CONCLUSION

NETF is as effective as JF in maintaining nutrition in patients with severe corrosive injury. The stricture development rate is similar, but nasoenteral tube placement provides a lumen for dilatation should a tight stricture develop.

摘要

背景

腐蚀性损伤患者的营养支持传统上通过全肠外营养(TPN)或空肠造口喂养(JF)来实现。目前尚无关于腐蚀性摄入患者进行鼻肠管喂养(NETF)的报道。

目的

我们报告了我们在鼻肠管喂养(NETF)方面的经验,并将这些患者的结果与接受 JF 的患者进行了比较。

设置

印度北部的一家三级医疗中心。

设计和干预

回顾了 53 例和 43 例分别接受 NETF 和 JF 的严重急性腐蚀性损伤患者的记录。所有患者均接受了 50kcal/kg、2g/kg 蛋白质匀浆液体饮食 8 周。在第 8 周进行了对比研究,并记录了住院时和第 8 周时的体重和血清白蛋白水平。

主要观察指标

第 8 周时体重和血清白蛋白的变化以及狭窄发生率。

结果

NETF 和 JF 组分别有 41 例(80.39%)和 36 例(83.72%)患者出现狭窄。两组食管狭窄(P =.71)和胃狭窄(P =.89)的发生率无显著差异。两组患者在第 8 周时血清白蛋白和体重均无明显变化。NETF 组的并发症发生率低于 JF 组。尽管 NETF 组的所有患者都有通畅的管腔,但 JF 组有 5 例完全梗阻,无法进行内镜干预。

局限性

回顾性研究设计。

结论

NETF 在维持严重腐蚀性损伤患者的营养方面与 JF 同样有效。狭窄发生率相似,但如果发生紧束性狭窄,鼻肠管放置可提供扩张的管腔。

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