Berthet B, Castellani P, Brioche M I, Assadourian R, Gauthier A
Department of Surgery, Hôpital de la Conception, Marseille, France.
Eur J Surg. 1996 Dec;162(12):951-5.
To describe our experience of treating severe corrosive burns of the upper gastrointestinal (GI) tract.
Open study.
Teaching hospital, France.
18 patients who had swallowed an alkaline substance (caustic soda in 10 cases) and 4 who had swallowed either hydrochloric or sulphuric acid.
Endoscopy was done a mean of 4 hours after the substance had been swallowed. 10 patients underwent oesophagogastrectomy without thoracotomy.
Morbidity and mortality.
4 of the 10 patients died and 3 developed postoperative complications. Of the 12 patients treated by feeding jejunostomy 7 developed stenosis that required operation and 3 developed stenosis that responded to dilatation. None of the 12 died.
Early oesophagoscopy allowed optimal management. Patients died if they swallowed more than 60 ml of a strong alkaline substance. When patients are treated conservatively about half will develop stenoses that require operation.
描述我们治疗上消化道严重腐蚀性烧伤的经验。
开放性研究。
法国的教学医院。
18例吞服碱性物质（10例为烧碱）的患者和4例吞服盐酸或硫酸的患者。
吞服物质后平均4小时进行内镜检查。10例患者接受了非开胸食管胃切除术。
发病率和死亡率。
10例患者中有4例死亡，3例出现术后并发症。在12例行空肠造口喂养治疗的患者中，7例出现需要手术治疗的狭窄，3例出现对扩张治疗有反应的狭窄。12例患者均未死亡。
早期食管镜检查有助于进行最佳治疗。如果患者吞服超过60毫升的强碱性物质，就会死亡。当对患者进行保守治疗时，约一半患者会出现需要手术治疗的狭窄。
