涡虫再生中的新出现模式。
Emerging patterns in planarian regeneration.
作者信息
Forsthoefel David J, Newmark Phillip A
机构信息
Howard Hughes Medical Institute, Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, 601 S. Goodwin Avenue, B107 CLSL, Urbana, IL 61801, United States.
出版信息
Curr Opin Genet Dev. 2009 Aug;19(4):412-20. doi: 10.1016/j.gde.2009.05.003. Epub 2009 Jul 1.
Abstract
In the past decade, the planarian has become an increasingly tractable invertebrate model for the investigation of regeneration and stem cell biology. Application of a variety of techniques and development of genomic reagents in this system have enabled exploration of the molecular mechanisms by which pluripotent somatic stem cells called neoblasts replenish, repair, and regenerate planarian tissues and organs. Recent investigations have implicated evolutionarily conserved signaling pathways in the re-establishment of anterior-posterior (A-P), dorsal-ventral (D-V), and medial-lateral (M-L) polarity after injury. These studies have significantly advanced our understanding of early events during planarian regeneration and have raised new questions about the mechanisms of stem cell-based tissue repair and renewal.
摘要
在过去十年中，涡虫已成为用于研究再生和干细胞生物学的越来越易于处理的无脊椎动物模型。在这个系统中应用各种技术和开发基因组试剂，使得人们能够探索多能性体细胞干细胞（称为新生细胞）补充、修复和再生涡虫组织和器官的分子机制。最近的研究表明，进化上保守的信号通路参与了损伤后前后（A-P）、背腹（D-V）和内外（M-L）极性的重建。这些研究显著推进了我们对涡虫再生早期事件的理解，并提出了关于基于干细胞的组织修复和更新机制的新问题。
相似文献
1
Emerging patterns in planarian regeneration.涡虫再生中的新出现模式。
Curr Opin Genet Dev. 2009 Aug;19(4):412-20. doi: 10.1016/j.gde.2009.05.003. Epub 2009 Jul 1.
2
Stem Cells, Patterning and Regeneration in Planarians: Self-Organization at the Organismal Scale.涡虫中的干细胞、模式形成与再生：机体尺度上的自组织
Methods Mol Biol. 2018;1774:57-172. doi: 10.1007/978-1-4939-7802-1_2.
3
Intercalary regeneration in planarians.涡虫的居间再生
Dev Dyn. 2003 Feb;226(2):308-16. doi: 10.1002/dvdy.10249.
4
The molecular logic for planarian regeneration along the anterior-posterior axis.沿前后轴的扁形动物再生的分子逻辑。
Nature. 2013 Aug 1;500(7460):73-6. doi: 10.1038/nature12359. Epub 2013 Jul 24.
5
Follistatin antagonizes activin signaling and acts with notum to direct planarian head regeneration.Follistatin 拮抗激活素信号，并与 notum 一起作用指导扁形动物头部再生。
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1363-8. doi: 10.1073/pnas.1214053110. Epub 2013 Jan 7.
6
Regeneration in an evolutionarily primitive brain--the planarian Dugesia japonica model.在进化上较为原始的大脑中进行再生——以日本三角涡虫为模型。
Eur J Neurosci. 2011 Sep;34(6):863-9. doi: 10.1111/j.1460-9568.2011.07819.x.
7
Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration.c-Jun N-末端激酶激活在水螅再生中的芽基形成中的作用。
Dev Growth Differ. 2011 Apr;53(3):389-400. doi: 10.1111/j.1440-169X.2011.01254.x. Epub 2011 Mar 30.
8
Evolution and regeneration of the planarian central nervous system.涡虫中枢神经系统的进化与再生。
Dev Growth Differ. 2009 Apr;51(3):185-95. doi: 10.1111/j.1440-169X.2009.01099.x.
9
Planarian Hedgehog/Patched establishes anterior-posterior polarity by regulating Wnt signaling.涡虫 Hedgehog/Patched 通过调节 Wnt 信号建立前后极性。
Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22329-34. doi: 10.1073/pnas.0907464106. Epub 2009 Dec 11.
10
pbx is required for pole and eye regeneration in planarians.pbx 对于涡虫的杆和眼再生是必需的。
Development. 2013 Feb;140(4):719-29. doi: 10.1242/dev.083741. Epub 2013 Jan 14.
引用本文的文献
1
An insight into planarian regeneration.对扁形动物再生的深入了解。
Cell Prolif. 2022 Sep;55(9):e13276. doi: 10.1111/cpr.13276. Epub 2022 Jul 10.
2
The Diverse Manifestations of Regeneration and Why We Need to Study Them.再生的多样表现形式以及我们为何需要对其进行研究。
Cold Spring Harb Perspect Biol. 2021 Nov 8;14(9). doi: 10.1101/cshperspect.a040931.
3
Different classes of small RNAs are essential for head regeneration in the planarian Dugesia japonica.不同种类的小 RNA 对于日本三角涡虫的头部再生是必不可少的。
BMC Genomics. 2020 Dec 7;21(1):876. doi: 10.1186/s12864-020-07234-1.
4
Extreme Environmental Stress-Induced Biological Responses in the Planarian.涡虫极端环境应激诱导的生物学响应。
Biomed Res Int. 2020 Jun 11;2020:7164230. doi: 10.1155/2020/7164230. eCollection 2020.
5
Cell-type diversity and regionalized gene expression in the planarian intestine.涡虫肠道中的细胞多样性和区域化基因表达。
Elife. 2020 Apr 2;9:e52613. doi: 10.7554/eLife.52613.
6
Regeneration in the ctenophore Mnemiopsis leidyi occurs in the absence of a blastema, requires cell division, and is temporally separable from wound healing.栉水母门Mnemiopsis leidyi 的再生过程在没有芽基的情况下发生，需要细胞分裂，并且在时间上与创伤愈合过程可分。
BMC Biol. 2019 Oct 11;17(1):80. doi: 10.1186/s12915-019-0695-8.
7
Nuclear receptor NR4A is required for patterning at the ends of the planarian anterior-posterior axis.核受体 NR4A 对于扁形动物前后轴末端的模式形成是必需的。
Elife. 2019 Apr 26;8:e42015. doi: 10.7554/eLife.42015.
8
Generic wound signals initiate regeneration in missing-tissue contexts.通用的伤口信号在缺失组织的情况下启动再生。
Nat Commun. 2017 Dec 22;8(1):2282. doi: 10.1038/s41467-017-02338-x.
9
Cloning and expression analysis of BmYki gene in silkworm, Bombyx mori.家蚕BmYki基因的克隆与表达分析
PLoS One. 2017 Aug 9;12(8):e0182690. doi: 10.1371/journal.pone.0182690. eCollection 2017.
10
Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration.整合素抑制涡虫再生过程中的神经发生并调节脑组织组装。
Development. 2017 Mar 1;144(5):784-794. doi: 10.1242/dev.139964. Epub 2017 Jan 26.
本文引用的文献
1
THE DYNAMICS OF WOUND CLOSURE AND ITS ROLE IN THE PROGRAMMING OF PLANARIAN REGENERATION I-BLASTEMA EMERGENCE.伤口闭合的动力学及其在涡虫再生编程中的作用I——芽基的出现
Dev Growth Differ. 1979;21(3):195-204. doi: 10.1111/j.1440-169X.1979.00195.x.
2
Regeneration: The origin of cancer or a possible cure?再生：癌症的起源还是一种可能的治愈方法？
Semin Cell Dev Biol. 2009 Jul;20(5):557-64. doi: 10.1016/j.semcdb.2009.04.005. Epub 2009 Apr 14.
3
Flow cytometry methods for the study of cell-cycle parameters of planarian stem cells.用于研究涡虫干细胞细胞周期参数的流式细胞术方法。
Dev Dyn. 2009 May;238(5):1111-7. doi: 10.1002/dvdy.21928.
4
Planarian regeneration: achievements and future directions after 20 years of research.涡虫再生：20年研究后的成果与未来方向
Int J Dev Biol. 2009;53(8-10):1317-27. doi: 10.1387/ijdb.072414es.
5
Multiple Wnts are involved in Hydra organizer formation and regeneration.多种Wnt信号参与水螅组织者的形成和再生。
Dev Biol. 2009 Jun 1;330(1):186-99. doi: 10.1016/j.ydbio.2009.02.004. Epub 2009 Feb 13.
6
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration.在涡虫再生过程中，Smed-Evi/Wntless对于β-连环蛋白依赖性和非依赖性过程都是必需的。
Development. 2009 Mar;136(6):905-10. doi: 10.1242/dev.033761. Epub 2009 Feb 11.
7
Autophagy in freshwater planarians.淡水涡虫中的自噬作用。
Methods Enzymol. 2008;451:439-65. doi: 10.1016/S0076-6879(08)03227-8.
8
Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea.扩展的头蛋白基因家族在涡虫地中海涡虫中的表达模式
Gene Expr Patterns. 2009 Apr;9(4):246-53. doi: 10.1016/j.gep.2008.12.008. Epub 2009 Jan 12.
9
Formaldehyde-based whole-mount in situ hybridization method for planarians.涡虫基于甲醛的全胚胎原位杂交方法
Dev Dyn. 2009 Feb;238(2):443-50. doi: 10.1002/dvdy.21849.
10
Beta-catenin and axis formation in planarians.β-连环蛋白与涡虫的轴形成
Bioessays. 2009 Jan;31(1):5-9. doi: 10.1002/bies.080193.
Zotero 插件