Webb Andrew G, Neuberger Thomas, Park Eun-Joo, Smith Nadine
Department of Bioengineering, The Pennsylvania State University, University Park, PA, USA.
IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Jun;56(6):1145-50. doi: 10.1109/TUFFC.2009.1156.
Magnetic resonance imaging (MRI)-based temperature mapping very close to the surface of an ultrasound transducer is not possible due to the large magnetic susceptibility- induced image artifacts that arise from the materials used in transducer construction. Here, it is shown in phantoms that "susceptibility-compensated" MRI sequences can be used to measure thermal increases approximately 1 mm from the surface of a 4-element cymbal array transducer, which has been used widely for noninvasive transdermal drug delivery. The estimated temperatures agree well with those measured using thermocouples.
基于磁共振成像(MRI)的温度测绘无法在非常靠近超声换能器表面的位置进行,这是因为换能器构造中所使用的材料会产生较大的磁化率诱导图像伪影。在此,通过体模实验表明,“磁化率补偿”MRI序列可用于测量距四元件钹形阵列换能器表面约1毫米处的温度升高,该换能器已广泛用于无创经皮给药。估计温度与使用热电偶测量的温度非常吻合。