疾病状态下血清和血浆基质金属蛋白酶（MMP）-2或MMP-9水平之间的正相关关系。 - Suppr

Positive correlations between serum and plasma matrix metalloproteinase (MMP)-2 or MMP-9 levels in disease conditions.

作者信息

Gerlach Raquel F, Meschiari Cesar A, Marcaccini Andrea M, Palei Ana C T, Sandrim Valeria C, Cavalli Ricardo C, Tanus-Santos Jose E

出版信息

Clin Chem Lab Med. 2009;47(7):888-91. doi: 10.1515/CCLM.2009.203.

DOI:10.1515/CCLM.2009.203

PMID:19575552

Abstract

摘要

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Positive correlations between serum and plasma matrix metalloproteinase (MMP)-2 or MMP-9 levels in disease conditions.疾病状态下血清和血浆基质金属蛋白酶（MMP）-2或MMP-9水平之间的正相关关系。

Clin Chem Lab Med. 2009;47(7):888-91. doi: 10.1515/CCLM.2009.203.

Serum matrix metalloproteinases -2, -9 and tissue inhibitors of metalloproteinases -1, -2 in lung cancer--TIMP-1 as a prognostic marker.肺癌中血清基质金属蛋白酶-2、-9及金属蛋白酶组织抑制剂-1、-2——TIMP-1作为一种预后标志物

Anticancer Res. 2000 Mar-Apr;20(2B):1311-6.

Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma.血清的快速分离并不能避免血清中基质金属蛋白酶（MMP）-9水平相对于血浆出现人为升高的情况。

Clin Biochem. 2007 Jan;40(1-2):119-23. doi: 10.1016/j.clinbiochem.2006.10.007. Epub 2006 Oct 19.

Assessment of gelatinase and tumor necrosis factor-α level in the vitreous and serum of patients with Eales disease: role of inflammation-mediated angiogenesis in the pathogenesis of Eales disease.评估 Eales 病患者玻璃体液和血清中明胶酶和肿瘤坏死因子-α水平：炎症介导的血管生成在 Eales 病发病机制中的作用。

Retina. 2011 Jul-Aug;31(7):1412-20. doi: 10.1097/IAE.0b013e318203c199.

Matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases 1 and 2 as potential biomarkers for gestational hypertension.基质金属蛋白酶-9 和金属蛋白酶组织抑制剂 1 和 2 作为妊娠期高血压的潜在生物标志物。

Singapore Med J. 2012 Oct;53(10):681-3.

Mercury exposure increases circulating net matrix metalloproteinase (MMP)-2 and MMP-9 activities.汞暴露会增加循环净基质金属蛋白酶（MMP）-2 和 MMP-9 的活性。

Basic Clin Pharmacol Toxicol. 2009 Oct;105(4):281-8. doi: 10.1111/j.1742-7843.2009.00443.x. Epub 2009 Jul 6.

Circulating matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases-1 and -2 levels in gestational hypertension.妊娠期高血压患者循环中基质金属蛋白酶-9及金属蛋白酶组织抑制剂-1和-2的水平

Am J Hypertens. 2005 Mar;18(3):325-9. doi: 10.1016/j.amjhyper.2004.09.014.

MMP-2 and MMP-9 and their tissue inhibitors in the plasma of preterm and term neonates.早产和足月新生儿血浆中的基质金属蛋白酶-2、基质金属蛋白酶-9及其组织抑制剂

Pediatr Res. 2004 May;55(5):794-801. doi: 10.1203/01.PDR.0000120683.68630.FB. Epub 2004 Feb 18.

Effect of hemodialysis on the plasma level of type IV collagenases and their inhibitors.

Clin Biochem. 2002 Jul;35(5):383-8. doi: 10.1016/s0009-9120(02)00331-4.

Gelatinase A (MM-2), gelatinase B (MMP-9) and their inhibitors (TIMP 1, TIMP-2) in serum of women with endometriosis: Significant correlation between MMP-2, MMP-9 and their inhibitors without difference in levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in relation to the severity of endometriosis.子宫内膜异位症女性血清中的明胶酶A（MM-2）、明胶酶B（MMP-9）及其抑制剂（TIMP 1、TIMP-2）：MMP-2、MMP-9与其抑制剂之间存在显著相关性，基质金属蛋白酶和金属蛋白酶组织抑制剂水平与子宫内膜异位症严重程度无关。

Gynecol Endocrinol. 2008 Jun;24(6):326-30. doi: 10.1080/09513590802090325.

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Using Zymography to Assess Circulating Matrix Metalloproteinase (MMP)-2 and MMP-9 in Clinical Samples.使用酶谱法评估临床样本中循环基质金属蛋白酶（MMP）-2和MMP-9

Methods Mol Biol. 2025;2918:177-186. doi: 10.1007/978-1-0716-4482-9_14.

Circulating Transforming Growth Factor-β and Aortic Dilation in Patients with Repaired Congenital Heart Disease.循环转化生长因子-β与先天性心脏病修复术后患者的主动脉扩张。

Sci Rep. 2019 Jan 17;9(1):162. doi: 10.1038/s41598-018-36458-1.

Serum or Plasma Matrix Metalloproteinase (MMP)-9 Levels and Cardiovascular Diseases.血清或血浆基质金属蛋白酶（MMP）-9水平与心血管疾病

J Cardiovasc Transl Res. 2018 Dec;11(6):524-525. doi: 10.1007/s12265-018-9827-8. Epub 2018 Aug 21.

Levels of matrix metalloproteinases differ in plasma and serum - aspects regarding analysis of biological markers in cancer.基质金属蛋白酶在血浆和血清中的水平存在差异——癌症生物标志物分析的相关方面。

Br J Cancer. 2016 Sep 6;115(6):703-6. doi: 10.1038/bjc.2016.127. Epub 2016 May 17.

Reappraisal of quantitative gel zymography for matrix metalloproteinases.基质金属蛋白酶定量凝胶酶谱法的重新评估

J Clin Lab Anal. 2014 Sep;28(5):374-80. doi: 10.1002/jcla.21696. Epub 2014 Mar 19.

Pre-treatment gelatinases' serum levels and post-treatment changes in laryngeal cancer patients.喉癌患者治疗前明胶酶的血清水平及治疗后的变化

Hippokratia. 2013 Jul;17(3):220-7.

Serum MMP-8: a novel indicator of left ventricular remodeling and cardiac outcome in patients after acute myocardial infarction.血清 MMP-8：急性心肌梗死后患者左心室重构和心脏结局的新指标。

PLoS One. 2013 Aug 14;8(8):e71280. doi: 10.1371/journal.pone.0071280. eCollection 2013.

The behavior of matrix metalloproteinases and their inhibitors in colorectal cancer.基质金属蛋白酶及其抑制剂在结直肠癌中的行为

Int J Mol Sci. 2012 Oct 16;13(10):13240-63. doi: 10.3390/ijms131013240.

Serum matrix metalloproteinase 9 and colorectal neoplasia: a community-based evaluation of a potential diagnostic test.血清基质金属蛋白酶 9 与结直肠肿瘤：一项基于社区的潜在诊断检测评估。

Br J Cancer. 2012 Apr 10;106(8):1431-8. doi: 10.1038/bjc.2012.93. Epub 2012 Mar 20.

Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer.术前血清中基质金属蛋白酶-2（MMP-2）和-9（MMP-9）作为结直肠癌患者的独立预后标志物。

Mol Cell Biochem. 2011 Sep;355(1-2):173-8. doi: 10.1007/s11010-011-0851-0. Epub 2011 May 4.

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Positive correlations between serum and plasma matrix metalloproteinase (MMP)-2 or MMP-9 levels in disease conditions.

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