Bi Qi, Wang Li-Feng, Song Zhe
Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
Zhonghua Nei Ke Za Zhi. 2009 Mar;48(3):213-5.
To assess the incidence, types and risk factors of atherothrombotic events (AT) within 7 days after transient ischemic attack (TIA) with ABCD2 Score in Chinese patients.
With ABCD2 Score, we retrospectively reviewed the medical records of 198 TIA patients, which met the inclusion criteria of our study. They were divided into a low risk group (ABCD2 < or = 3) and a moderate-high risk group (ABCD2 > or = 4) and the incidence, types and risk factors of AT within 7 days after TIA were evaluated and compared respectively with chi(2) test between the two groups. Statistic significance was considered as P < 0.05.
The order of the frequency of accompanying diseases was hypertension 68.18% (135/198), diabetes 23.74% (47/198), coronary artery disease 21.72% (43/198), ischemic stroke 15.66% (31/198) and hyperlipemia 12.63% (25/198). AT within 7 days after TIA was observed in 6.19% (6/97) of the patients in the low risk group, all of them were suffering from TIA recurrence. In the moderate-high risk group, 14.85% (15/101) of the patients experienced AT, including 2 cases of TIA recurrence, 10 cases of ischemic stroke, 1 case of both TIA recurrence and ischemic stroke, 1 case of angina pectoris and 1 case of myocardial infarction. There was no peripheral vascular disease or death from vascular disease. Incidence of AT within 7 days in the moderate-high risk group was significantly higher than that in the low risk group (51.70% vs 27.27%, P < 0.05).
TIA patients with ABCD2 > or = 4 are at higher risk of AT within 7 days after TIA onset.
采用ABCD2评分评估中国短暂性脑缺血发作（TIA）患者在发作后7天内动脉粥样硬化血栓形成事件（AT）的发生率、类型及危险因素。
采用ABCD2评分，回顾性分析198例符合本研究纳入标准的TIA患者的病历资料。将患者分为低危组（ABCD2≤3）和中高危组（ABCD2≥4），分别评估TIA后7天内AT的发生率、类型及危险因素，并采用卡方检验对两组进行比较。以P<0.05为差异有统计学意义。
伴随疾病的发生率依次为高血压68.18%（135/198）、糖尿病23.74%（47/198）、冠状动脉疾病21.72%（43/198）、缺血性卒中15.66%（31/198）和高脂血症12.63%（25/198）。低危组6.19%（6/97）的患者在TIA后7天内发生AT，均为TIA复发。中高危组14.85%（15/101）的患者发生AT，包括2例TIA复发、10例缺血性卒中、1例TIA复发合并缺血性卒中、1例心绞痛和1例心肌梗死。无周围血管疾病或血管疾病死亡病例。中高危组TIA后7天内AT的发生率显著高于低危组（51.70%对27.27%，P<0.05）。
ABCD2≥4的TIA患者在TIA发作后7天内发生AT的风险较高。
