[大肠身心病理学的心理学方面]

[Psychological aspects of psychosomatic pathology of large intestine].

作者信息

Vashadze Sh V

出版信息

Georgian Med News. 2009 Jun(171):37-40.

PMID:19578211

Abstract

One of the most widespread aspects of psychosomatic pathology of gastrointestinal tract is irritable bowel syndrome (IBS). Over 70% of functional pathology of large intestine falls at IBS. The aim of the investigation was the assessment of depression rate in patients with IBS. Taking into consideration the age of individuals, 100 patients 50 men and 50 women aged 21 to 75 years were examined by using clinical, psychological and statistic (correlation) analysis to determine whether there were relations between clinical manifestations of the irritable bowel syndrome and personality. Diarrhea variant of IBS syndrome was detected in 17 (34%) men and in 21 (42%) females. Diarrhea and pain variant of IBS syndrome was detected in 12 (24%) men and 17 (34%) female. Pain variant of IBS syndrome was detected in 5 (10%) men and 12 (24%) females. Constipation variant was detected in 16 (32%) men and 3 (6%) female. In 84% of patients with IBS was found dysphoria; weight loss and bed appetite - in 44%, insomnia - in 40%, general lethargy and adynamia - in 80%; loss of interest - in 38%; asthenia - in 70%, devoured by guilt - 43%, uncertainty - 80%. Depression in patients with IBS was treated with serotonin selective antidepressants. Investigation revealed that the best result is achieved with serotonin-selective antidepressant therapy.

摘要

胃肠道心身病理学最普遍的方面之一是肠易激综合征（IBS）。超过70%的大肠功能性病变属于IBS。本研究的目的是评估IBS患者的抑郁率。考虑到个体年龄，对100名年龄在21至75岁之间的患者（50名男性和50名女性）进行了临床、心理和统计学（相关性）分析，以确定肠易激综合征的临床表现与性格之间是否存在关联。在17名（34%）男性和21名（42%）女性中检测到IBS综合征的腹泻型。在12名（24%）男性和17名（34%）女性中检测到IBS综合征的腹泻和疼痛型。在5名（10%）男性和12名（24%）女性中检测到IBS综合征的疼痛型。在16名（32%）男性和3名（6%）女性中检测到便秘型。在84%的IBS患者中发现烦躁不安；体重减轻和食欲不振——44%，失眠——40%，全身倦怠和乏力——80%；兴趣丧失——38%；虚弱——70%，内疚感强烈——43%，不确定感——80%。IBS患者的抑郁症用血清素选择性抗抑郁药治疗。研究表明，血清素选择性抗抑郁药治疗取得了最佳效果。