Paterok E M, Rummel W D, Weishaar J
Dtsch Med Wochenschr. 1977 Jul 1;102(26):960-2. doi: 10.1055/s-0028-1104997.
In 614 breasts tumours assumed to be harmless cysts on palpation were aspirated. In 430 cases aspiration was the definitive treatment. In the other 184 cases excision was necessary in order to obtain histology. 11 cysts were radiologically suspect after air filling. In one case excision demonstrated an undifferentiated milk duct carcinoma. 12 cysts had radiologically suspicious areas outside their margins. In 4 cases lobular carcinoma in situ was present. 161 excisions were necessary because no fluid was aspirated at puncture of the tumour. In 10 cases histology showed malignancy: half of these were metastases from a known primary tumour and half were primary breast carcinomas. Out of 17 precancerous states neoplasia could be demonstrated in two cases in addition to papillary and proliferative duct changes. We have classified this neoplasia as lobular carcinoma in situ.
对614例经触诊认为是无害囊肿的乳腺肿瘤进行了抽吸。430例中,抽吸是最终治疗方法。在另外184例中,为了获得组织学结果有必要进行切除。11个囊肿在注入空气后在放射学上可疑。1例切除显示为未分化乳腺导管癌。12个囊肿在其边缘外有放射学上可疑区域。4例存在小叶原位癌。161例因在肿瘤穿刺时未抽出液体而需要切除。10例组织学显示为恶性:其中一半是已知原发肿瘤的转移灶,一半是原发性乳腺癌。在17例癌前状态中,除了乳头状和增生性导管改变外,在2例中证实有肿瘤形成。我们将这种肿瘤形成归类为小叶原位癌。