Intussusception presenting as lethargy in a 6-month-old infant.

A case of intussusception in a 6 month old with lethargy as the initial and predominant system is presented. Children presented to the Emergency Department with otherwise unexplained lethargy should have intussusception as part of the differential diagnosis. A plain film of the abdomen should be obtained. A rectal exam should be done, and a stool checked for occult blood. Radiologic and surgical consultation should be sought simultaneously. Delay in diagnosis and treatment may be associated with decreased success rates of reduction by barium enema, and increased rates of complications of perforation, peritonitis, sepsis, and death.