Cormier B, Serafini D, Grimberg D, Scheuer B, Acar J
Service de cardiologie, hôpital Tenon, Paris.
Arch Mal Coeur Vaiss. 1991 Sep;84(9):1321-6.
This retrospective study assessed the prevalence of left atrial thrombi in mitral stenosis and evaluated the diagnostic value ot the main means of investigation Five hundred and eighty-one patients underwent open heart surgery over a 10 year period. The prevalence of atrial thrombi was 7%, the majority (60%) being located in the left atrial appendage. The sensitivity of transthoracic echocardiography for detecting thrombi in the left atrial cavity was satisfactory (65%) but was very poor for detecting thrombi in the left atrial appendage (4%). The results of invasive investigations (atrial angiography and coronary angiography) are no better. Without any doubt, transoesophageal echocardiography, performed in 101 patients in this series, has transformed these results (sensitivity 83%, specificity 97%). False negatives in this study mainly concerned small thrombi adherent to the atrial wall. Under these conditions, it would seem reasonable to propose transoesophageal echocardiography to all patients with mitral stenosis complicated by an embolic event or for those for whom percutaneous commissurotomy is suggested.
这项回顾性研究评估了二尖瓣狭窄患者左心房血栓的患病率,并评估了主要检查手段的诊断价值。在10年期间,581例患者接受了心脏直视手术。心房血栓的患病率为7%,大多数(60%)位于左心耳。经胸超声心动图检测左心房腔内血栓的敏感性令人满意(65%),但检测左心耳内血栓的敏感性很差(4%)。侵入性检查(心房血管造影和冠状动脉造影)的结果也没有更好。毫无疑问,本系列中101例患者接受的经食管超声心动图改变了这些结果(敏感性83%,特异性97%)。本研究中的假阴性主要涉及附着于心房壁的小血栓。在这种情况下,对所有合并栓塞事件的二尖瓣狭窄患者或建议进行经皮球囊二尖瓣成形术的患者建议行经食管超声心动图检查似乎是合理的。