Department of Rheumatology, Hospital Clinico Universitario, Santiago de Compostela, Spain.
Rheumatol Int. 2010 Jul;30(9):1227-9. doi: 10.1007/s00296-009-1042-0. Epub 2009 Jul 7.
Non-secretory myeloma is a plasma cell dyscrasia characterized by the absence of serum and urinary monoclonal immunoglobulins on electrophoretic tests. Because of the lack of monoclonal protein, the identification of the disease is more difficult than for secretory myelomas. The coexistence of ankylosing spondylitis and multiple myeloma has been reported occasionally. We report a rare case of oligo-secretory myeloma coexistent with ankylosing spondylitis.
非分泌型骨髓瘤是一种浆细胞恶性增生性疾病,其特征是电泳检测时血清和尿液中无单克隆免疫球蛋白。由于缺乏单克隆蛋白,因此与分泌型骨髓瘤相比,该病的诊断更为困难。曾有报道称强直性脊柱炎与多发性骨髓瘤偶有共存。我们报告一例罕见的寡分泌型骨髓瘤合并强直性脊柱炎的病例。