McCluskey P, Wakefield D
Laboratory of Ocular Immunology, School of Pathology, University of NSW, Australia.
Aust N Z J Ophthalmol. 1991 Aug;19(3):211-5. doi: 10.1111/j.1442-9071.1991.tb00663.x.
Scleritis is a severe chronic inflammation of the eye wall. High-dose corticosteroids and other immunosuppressive drugs are often required to control the inflammatory process. With the development of new and potentially more effective treatment modalities for scleritis has emerged the need for an accurate and reproducible system for quantifying the severity of scleritis and evaluating the response of individual patients to treatment. We have developed a quantitative scoring system, based on common clinical signs of scleritis, and evaluated it in 24 patients with scleritis. Our results indicate that this system is simple, rapid, reproducible and useful in grading the severity of scleritis and in predicting the response of patients to systemic immunosuppressive therapy.
巩膜炎是一种严重的眼壁慢性炎症。通常需要大剂量皮质类固醇和其他免疫抑制药物来控制炎症过程。随着针对巩膜炎的新的且可能更有效的治疗方式的发展，出现了对一种准确且可重复的系统的需求，该系统用于量化巩膜炎的严重程度并评估个体患者对治疗的反应。我们基于巩膜炎的常见临床体征开发了一种定量评分系统，并在24例巩膜炎患者中对其进行了评估。我们的结果表明，该系统在对巩膜炎严重程度进行分级以及预测患者对全身免疫抑制治疗的反应方面简单、快速、可重复且有用。
