Narodetskaia R V, Gadzhieva Z M, Makarova L F, Solov'eva G I, Nesterin M F
Farmakol Toksikol. 1976 Sep-Oct;39(5):619-22.
In tests set up on rats the effect of methandrostenolone on the external secretion of the liver, fermentative activity of the pancreatic tissue and histological and hisochemical findings subsequent to an investigation of internal organs were studied. Introduction of methandrostenolone led to changes in bilification and to a reduced concentration basic components of the bile, to a distinctly pronounced rise in the level of the trypsin inhibitor and to a depressed activity of trypsin in the pancreatic tissue. It also resulted in a change of histochemical and fermentative indices in the tissue of the liver, spleen and other organs.
在对大鼠进行的实验中，研究了美雄酮对肝脏外分泌、胰腺组织发酵活性以及对内脏器官进行调查后的组织学和组织化学结果的影响。注射美雄酮导致胆色素形成发生变化，胆汁中碱性成分浓度降低，胰蛋白酶抑制剂水平明显升高，胰腺组织中胰蛋白酶活性受到抑制。它还导致肝脏、脾脏和其他器官组织中的组织化学和发酵指标发生变化。
