Oukabli M, Akhaddar A, Qamouss O, Chahdi H, Rimani M, Albouzidi A
Hôpital militaire d'instruction Mohamed V, Hay Riad, 10000 Rabat, Maroc.
Rev Stomatol Chir Maxillofac. 2010 Feb;111(1):43-5. doi: 10.1016/j.stomax.2009.05.002. Epub 2009 Jul 7.
Psammomatoid cemento-ossifying fibroma (PCOF) is a rare benign fibro-osseous lesion. It affects the maxilla, the nasal cavity, paranasal sinuses, and the ethmoid. It is slow-growing, progressive, and benign but it can be locally extended and mimic a malignant tumor.
We report the unusual case of a 36-year-old woman with a nasal and ethmoid PCOF with orbital and endocranial extension. The tumor was revealed by exophthalmia and nasal obstruction. The diagnosis was proven histologicaly on biopsies. The treatment was transfacial surgery. There was no recurrence 1 year later.
Intraorbital and endocranial extension of PCOF are rare aggressive behaviours. Histologically, the differential diagnosis is difficult between fibrous dysplasia or psammomatoid meningioma. Complete surgical excision is necessary to prevent recurrence.
砂粒样骨化纤维瘤（PCOF）是一种罕见的良性纤维-骨病变。它可累及上颌骨、鼻腔、鼻窦和筛骨。其生长缓慢、呈进行性且为良性，但可局部扩展并类似恶性肿瘤。
我们报告了一例36岁女性的罕见病例，该患者患有累及鼻腔和筛骨的PCOF，并伴有眼眶和颅内扩展。肿瘤表现为眼球突出和鼻塞。活检经组织学检查确诊。治疗采用经面部手术。1年后无复发。
PCOF的眼眶和颅内扩展是罕见的侵袭性行为。在组织学上，纤维发育不良或砂粒样脑膜瘤之间的鉴别诊断较为困难。为防止复发，完全手术切除是必要的。
