Ditkoff E C, Lobo R A
University of Southern California School of Medicine, Los Angeles.
Curr Opin Obstet Gynecol. 1991 Oct;3(5):635-40.
Papers related to ovarian stimulation for in vitro fertilization were reviewed from the period of April 1990 to March 1991. Most of the literature pertained to regimens using gonadotropin-releasing hormone agonists. Other areas of interest included information on the impact of cryopreservation, norethindrone for cycle synchronization, and human chronic gonadotropin for luteal support during in vitro fertilization. The adjunctive use of growth hormone to increase ovarian responsivity was also reported on. The effect of ovarian stimulation on endometrial development during in vitro fertilization was also discussed. In general, although there are several new regimens for inducing multiple follicular development in in vitro fertilization, it appears that there is no consensus on an ideal regimen. This in large part is related to heterogeneity among patient populations.
对1990年4月至1991年3月期间有关体外受精卵巢刺激的论文进行了综述。大多数文献涉及使用促性腺激素释放激素激动剂的方案。其他感兴趣的领域包括冷冻保存的影响、用于周期同步的炔诺酮以及体外受精期间用于黄体支持的人绒毛膜促性腺激素的信息。也有关于使用生长激素辅助增加卵巢反应性的报道。还讨论了体外受精期间卵巢刺激对子宫内膜发育的影响。总体而言，尽管在体外受精中诱导多个卵泡发育有几种新方案，但似乎对于理想方案尚无共识。这在很大程度上与患者群体的异质性有关。
