Clarke Alex, Butler Peter Em
Department of Plastic and Reconstructive Surgery, Royal Free Hospital, Pond Street, London NW3 2QG, UK.
Expert Rev Neurother. 2009 Jul;9(7):1087-100. doi: 10.1586/ern.09.42.
Facial transplantation is a major advance in reconstructive surgery, providing enormous potential benefit in terms of improved function and cosmesis. Managing the challenges it brings depends on understanding both technical and psychological issues. Research on the psychological aspects of organ transplantation is a starting point; however, issues of altered appearance and identity, adjustment to change, the management of suboptimal adherence to immunosuppression, and how we present and understand risk, particularly related to immunosuppression and rejection, must all be addressed before the procedure becomes a clinical option. This review addresses the psychological issues highlighted in the Royal College of Surgeons Working Party Report on facial transplantation, describing how these have been addressed in the development of a clinical program.
面部移植是整形手术的一项重大进展，在改善功能和美容方面具有巨大的潜在益处。应对其带来的挑战取决于对技术和心理问题的理解。器官移植心理方面的研究是一个起点；然而，在该手术成为临床选择之前，必须解决外观和身份改变、适应变化、对免疫抑制依从性欠佳的管理，以及我们如何呈现和理解风险（尤其是与免疫抑制和排斥相关的风险）等问题。本综述阐述了皇家外科医学院面部移植工作组报告中所强调的心理问题，并描述了在临床项目开展过程中是如何应对这些问题的。
