Cooper Julian, Flückiger Beat, Traichl Birgit, Diener Pierre-André, Otto Petra, von Kempis Johannes
Division of Rheumatology and Rehabilitation, Kantonsspital, St. Gallen, Rohrschacherstrasse 95, St. Gallen, Switzerland.
J Clin Rheumatol. 2009 Aug;15(5):244-6. doi: 10.1097/RHU.0b013e3181b12341.
In patients suffering from ankylosing spondylitis, silent inflammatory bowel disease (IBD) is frequent. Furthermore, spondylarthritis may be the first manifestation of IBD.We describe the case of a patient suffering from ankylosing spondylitis who presented with abdominal pain. The patient had been treated over 2(1/2) years with infliximab. Although the initial clinical presentation seemed to suggest new-onset IBD as the cause of the abdominal pain, it eventuated that the patient was suffering from a severe abdominal manifestation of tuberculosis likely due to reactivation of latent tuberculosis by the anti-TNF agent.
在强直性脊柱炎患者中，无症状性炎症性肠病（IBD）很常见。此外，脊柱关节炎可能是IBD的首发表现。我们描述了一例患有强直性脊柱炎且出现腹痛的患者病例。该患者接受英夫利昔单抗治疗超过两年半。尽管最初的临床表现似乎提示新发IBD是腹痛的原因，但最终发现该患者患有严重的腹部结核表现，可能是由于抗TNF药物激活了潜伏性结核。
