Bauer J, Landgraf S, Schrell U, Stefan H
Neurologische Klinik mit Poliklinik, Universität Erlangen-Nürnberg.
Dtsch Med Wochenschr. 1991 Nov 29;116(48):1824-7. doi: 10.1055/s-2008-1063824.
The prolactin concentration profile over 24 hours was determined in three men, aged 19, 27 and 43 years, who suffered from treatment-resistant complex-partial and (or) grand mal seizures of frontal lobe origin. All three patients were examined in the course of preoperative epilepsy diagnosis, the seizures being classified by video-EEG recordings, including subdural and sphenoidal foramen ovale electrodes. Seizures were recorded in all three patients (4 grand mal; 2 complex-partial), each of them followed by a rise in serum prolactin concentration (over 700 microU/ml). These findings contradict the theory that prolactin concentration rises only after temporal, not after frontal seizures. Knowing the postseizure serum prolactin concentration may help to distinguish frontal epileptic from psychogenic seizures.
对三名年龄分别为19岁、27岁和43岁的男性进行了24小时催乳素浓度曲线测定，这些男性患有起源于额叶的难治性复杂部分性发作和（或）全身性强直阵挛发作。所有三名患者均在术前癫痫诊断过程中接受检查，通过视频脑电图记录对发作进行分类，包括硬膜下电极和卵圆孔电极。三名患者均记录到发作（4次全身性强直阵挛发作；2次复杂部分性发作），每次发作后血清催乳素浓度均升高（超过700微单位/毫升）。这些发现与催乳素浓度仅在颞叶发作后升高而在额叶发作后不升高的理论相矛盾。了解发作后血清催乳素浓度可能有助于区分额叶癫痫和心因性发作。
