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[1223例肾移植中的泌尿系统并发症]

[Urological complications in 1223 kidney transplants].

作者信息

Nie Zhi-Lin, Li Qian-Sheng, Jin Feng-Shuo, Zhang Ke-Qin, Zhu Fang-Qiang, Huo Wen-Qian, Ma Qiang

机构信息

Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2009 May 12;89(18):1269-71.

Abstract

OBJECTIVE

To review retrospectively the urological complications in 1 223 kidney transplants.

METHODS

A total of 1 223 kidney transplants were divided into ureteroneocystostomy group (n = 948) and ureteroureterostomy group (n = 275) according to the methods of urinary tract reconstruction. The incidence and management of urological complications such as urinary fistula, obstruction of ureter, vesicoureteral reflux (VUR) and urinary tract infection (UTI) were summarized respectively.

RESULTS

Overall, urological complications were encountered in 217 (17.7%) cases, including 43 cases of urinary fistula (3.5%), 35 obstruction of ureter (2.9%), 14 VUR (1.1%) and 125 UTI (10.2%). Urinary fistula was 39 (4.1%) cases and 4 cases (1.5%) (P < 0.05), obstruction of ureter 22 (2.3%) & 13 (4.7%) (P < 0.05), VUR 14 (1.5%) & 0 (0%) (P < 0.05) and UTI 109 (11.5%) & 16 (5.8%) (P < 0.01) in the ureteroneocystostomy group and ureteroureterostomy group respectively. Seventy patients underwent surgical treatment. The 3-year survival rate of graft with urological complications and without urological complications were 82.3% and 84.7% respectively.

CONCLUSIONS

Ureteroureterostomy can decrease the incidence of urological complications after kidney transplantation. Most of urological complications require surgical interventions. The long-term graft survival is not affected by a correctly treated urological complication.

摘要

目的

回顾性分析1223例肾移植患者的泌尿系统并发症。

方法

根据尿路重建方法,将1223例肾移植患者分为输尿管膀胱吻合术组(n = 948)和输尿管输尿管吻合术组(n = 275)。分别总结尿瘘、输尿管梗阻、膀胱输尿管反流(VUR)和泌尿系统感染(UTI)等泌尿系统并发症的发生率及处理情况。

结果

总体而言,217例(17.7%)患者出现泌尿系统并发症,其中尿瘘43例(3.5%)、输尿管梗阻35例(2.9%)、VUR 14例(1.1%)、UTI 125例(10.2%)。输尿管膀胱吻合术组尿瘘39例(4.1%)、输尿管梗阻22例(2.3%)、VUR 14例(1.5%)、UTI 109例(11.5%);输尿管输尿管吻合术组尿瘘4例(1.5%)、输尿管梗阻13例(4.7%)、VUR 0例(0%)、UTI 16例(5.8%),差异均有统计学意义(P < 0.05或P < 0.01)。70例患者接受了手术治疗。有泌尿系统并发症和无泌尿系统并发症的移植肾3年生存率分别为82.3%和84.7%。

结论

输尿管输尿管吻合术可降低肾移植术后泌尿系统并发症的发生率。大多数泌尿系统并发症需要手术干预。正确处理的泌尿系统并发症不影响移植肾的长期存活。

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