鸡组织中HMG2补体变化的特征分析。

Characterization of HMG2 complement changes in chicken tissues.

作者信息

Boix J

机构信息

Department of Physiology, University of Barcelona School of Medicine, Spain.

出版信息

Exp Cell Res. 1991 Dec;197(2):333-4. doi: 10.1016/0014-4827(91)90443-x.

DOI:10.1016/0014-4827(91)90443-x

PMID:1959567

Abstract

Variations in the content of nonhistone proteins high mobility group 2a (HMG2a) and HMG2b have been determined in several cell types of chicken. HMG2a was found to accumulate during erythrocyte maturation. HMG2b is the major HMG2 subtype in testis and reaches the highest proportion, detected so far, in spermatid cells obtained by centrifugal elutriation. In hepatocytes HMG2b is barely detectable and HMG2a is the major subtype. In conclusion, the pattern of HMG2 composition is different in three quiescent and terminally differentiated cell types, no correlation between the state of cell proliferation and HMG2 composition can be established.

摘要

已测定鸡的几种细胞类型中非组蛋白高迁移率族蛋白2a（HMG2a）和HMG2b的含量变化。发现HMG2a在红细胞成熟过程中积累。HMG2b是睾丸中的主要HMG2亚型，在通过离心淘析获得的精子细胞中达到目前检测到的最高比例。在肝细胞中，HMG2b几乎检测不到，HMG2a是主要亚型。总之，HMG2组成模式在三种静止和终末分化细胞类型中有所不同，无法确定细胞增殖状态与HMG2组成之间的相关性。