Fujiu Koichi, Miyamoto Hideaki, Sakuma Hideo, Mori Masatoshi
Department of General Thoracic Surgery, Southern Tohoku General Hospital, 7-115 Yatsuyamada, Koriyama, Fukushima 963-8563, Japan.
Gen Thorac Cardiovasc Surg. 2009 Jul;57(7):382-4. doi: 10.1007/s11748-008-0402-0. Epub 2009 Jul 14.
A 29-year-old man presented with a mass in the left lower lung field on a chest radiograph obtained during a medical checkup. Computed tomography revealed a tumor adjacent to the diaphragm. A sessile tumor measuring 10.5 x 8.5 x 4.5 cm arising from the parietal pleura was resected. The tumor was accompanied by several little tumors on the nearby diaphragm. Pathologically, the major tumor consisted of typical spindle-shaped cells with myxoid degeneration. There was no increased cellularity, cellular pleomorphism, or a high mitotic count. In immunohistochemical studies, the spindle cells showed positive staining for CD34 and were negative for bcl-2. The smaller tumors also consisted of myxoid degeneration. We diagnosed benign solitary fibrous tumor of the pleura with satellite tumors. We must be aware of the possibility of satellite tumors when we treat patients with a benign solitary fibrous tumor.
一名29岁男性在体检时拍摄的胸部X光片显示左下肺野有一肿块。计算机断层扫描显示肿瘤毗邻膈肌。切除了一个起源于壁层胸膜、大小为10.5×8.5×4.5 cm的无蒂肿瘤。该肿瘤在附近的膈肌上伴有几个小肿瘤。病理检查显示,主要肿瘤由具有黏液样变性的典型梭形细胞组成。未见细胞增多、细胞异型性或高有丝分裂计数。免疫组化研究显示,梭形细胞CD34染色阳性,bcl-2染色阴性。较小的肿瘤也有黏液样变性。我们诊断为伴有卫星瘤的胸膜良性孤立性纤维瘤。在治疗胸膜良性孤立性纤维瘤患者时,我们必须意识到卫星瘤的可能性。