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严重病变的常见症状——胸膜巨大孤立性纤维瘤。

Ordinary symptom for a serious pathology - giant solitary fibrous tumor of the pleura.

作者信息

Bădilă Elisabeta, Grigore Cristina, Daraban Ana Maria, Ţintea Emma, Horvat Teodor, Davidescu Mihnea, Enache Valentin, Condrea Ileana, Bartoş Daniela, Popa Bogdan

机构信息

Clinical Emergency Hospital, Bucharest, Romania;

出版信息

Rom J Morphol Embryol. 2014;55(3 Suppl):1185-9.

Abstract

The solitary fibrous tumor of the pleura (SFTP) is a rare primary tumor arising from mesenchymal cells in the areolar tissue subjacent to the mesothelial-lined pleura. From an epidemiological standpoint, solitary fibrous tumors of the pleura account for less than 5% of primary pleural tumors, and commonly affect patients in the sixth and seventh decades. We presented the case of a 38-year-old woman, without any significant pathological history, who presented at the emergency room for unspecific respiratory symptoms. Imagistic investigations showed a giant opacity in the upper half part of the left hemithorax. The patient underwent surgery and en bloc resection of the tumor (30/25 cm) in oncological limits was performed. Definite diagnosis - solitary fibrous tumor of the pleura - was obtained through histological examination and immunohistochemistry. Even if SFTP are benign tumors, a long follow-up period is mandatory as even patients with complete resection are at risk of recurrence several years after surgery.

摘要

胸膜孤立性纤维瘤(SFTP)是一种罕见的原发性肿瘤,起源于间皮衬里胸膜下方疏松结缔组织中的间充质细胞。从流行病学角度来看,胸膜孤立性纤维瘤占原发性胸膜肿瘤的比例不到5%,常见于60至70岁的患者。我们报告了一例38岁女性病例,该患者无任何重大病史,因非特异性呼吸道症状就诊于急诊室。影像学检查显示左半胸上半部有巨大的不透明区。患者接受了手术,并在肿瘤学边界内对肿瘤(30/25厘米)进行了整块切除。通过组织学检查和免疫组化确诊为胸膜孤立性纤维瘤。即使SFTP是良性肿瘤,也必须进行长期随访,因为即使是完全切除的患者在术后数年仍有复发风险。

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