Zeigler V L, Peterson J
Division of Cardiovascular Nursing, Medical University of South Carolina, Charleston.
Heart Lung. 1991 Nov;20(6):689-91.
Class IC antiarrhythmic drugs, specifically encainide and flecainide, have been used with increasing frequency in children and young adults with both atrial and ventricular tachyarrhythmias. As a result of the recent findings from the Cardiac Arrhythmia Suppression Trial (CAST) study, their use in adults as well as children has been questioned. Because of their potential and often dangerous side effects, the child receiving a class IC drug must be monitored very closely. We report a case of flecainide toxicity in a 2 1/2-week-old neonate who was being treated for incessant supraventricular tachycardia.
Ic类抗心律失常药物，特别是恩卡胺和氟卡胺，在患有室上性和室性快速心律失常的儿童和年轻人中使用频率越来越高。心律失常抑制试验（CAST）研究的最新结果对其在成人和儿童中的应用提出了质疑。由于其潜在的且往往危险的副作用，接受Ic类药物治疗的儿童必须受到密切监测。我们报告了一例2.5周大的新生儿氟卡胺中毒病例，该新生儿正在接受持续性室上性心动过速的治疗。
