Banting Lee, Ahmed Sabbir
School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael's Building, White Swan Road, Portsmouth PO12DT, UK.
Anticancer Agents Med Chem. 2009 Jul;9(6):627-41. doi: 10.2174/187152009788680037.
The genetic control, mechanism of action and inhibition of aromatase for potential therapeutic benefits in the arena of hormone dependent illness continues to be of considerable interest. The work presented here concentrates on recent advances in the mechanistic aspects of the aromatase enzyme and the nature of the chemical entities that lead to its inhibition.
在激素依赖性疾病领域，芳香化酶的基因调控、作用机制以及抑制作用以获取潜在治疗益处一直备受关注。本文介绍的工作集中于芳香化酶的作用机制方面的最新进展以及导致其抑制的化学实体的性质。
