Doering Irene L, Richter Elmar
Walther Straub Institute, Department of Toxicology, Ludwig-Maximilians University, Munich, Germany.
Drug Metab Lett. 2009 Apr;3(2):83-6. doi: 10.2174/187231209788654045.
Myosmine, a minor tobacco alkaloid widely occurring in food products of plant and animal origin, inhibits the conversion of testosterone to estradiol by human aromatase (IC(50): 33+/-2 microM) sevenfold more potent than nicotine (IC(50): 223+/-10 microM) and may have implications for sexual hormone homoeostasis.
麦斯明是一种广泛存在于动植物源性食品中的微量烟草生物碱，它抑制人芳香化酶将睾酮转化为雌二醇的作用（半数抑制浓度[IC(50)]：33±2微摩尔），其效力比尼古丁（IC(50)：223±10微摩尔）强7倍，可能对性激素稳态有影响。
