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尿毒症患者及肾移植受者与对照组精液质量的比较研究。

Examination of the semen quality of patients with uraemia and renal transplant recipients in comparison with a control group.

作者信息

Xu L-G, Xu H-M, Zhu X-F, Jin L-M, Xu B, Wu Y, Lu N-Q

机构信息

The 117th Hospital, Hangzhou, Zhejiang, China.

出版信息

Andrologia. 2009 Aug;41(4):235-40. doi: 10.1111/j.1439-0272.2009.00924.x.

Abstract

To examine the semen quality of patients with uraemia and renal transplant recipients, 40 patients with uraemia and 40 renal transplant recipients were included. According to their interval of post-transplantation, renal transplant recipients were subdivided into group A (22) < or =2 years and group B (18) >2 years. A total of 40 healthy men with normal fertility were included as the controls. Semen samples from all subjects were collected and analysed. The fertility index (FI) value was calculated. The FI value of the normal fertility men was 13.02 (14.26), that of the renal transplant recipient groups A and B were 5.53 (8.30) and 9.27 (22.49) respectively, while the FI of the patients with uraemia was 0.23 (0.76). Compared with the uraemia group, the FI values of renal transplant recipient group either group A or group B were significantly better (P < 0.01). However, compared with the normal control group, the FI values of renal transplant recipient group A were lower (P < 0.01), while there was no significant difference between group B and the control group (P > 0.05). In conclusion, the FI of renal transplant recipients was recovered close to the level of healthy men with normal fertility 2 years after transplantation.

摘要

为研究尿毒症患者及肾移植受者的精液质量,纳入40例尿毒症患者和40例肾移植受者。肾移植受者根据移植后时间间隔分为A组(22例)≤2年和B组(18例)>2年。纳入40名生育能力正常的健康男性作为对照。收集并分析所有受试者的精液样本。计算生育指数(FI)值。生育能力正常男性的FI值为13.02(14.26),肾移植受者A组和B组的FI值分别为5.53(8.30)和9.27(22.49),而尿毒症患者的FI值为0.23(0.76)。与尿毒症组相比,肾移植受者A组或B组的FI值均显著更好(P<0.01)。然而,与正常对照组相比,肾移植受者A组的FI值较低(P<0.01),而B组与对照组之间无显著差异(P>0.05)。总之,肾移植受者的FI在移植后2年恢复至接近生育能力正常的健康男性水平。

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