Shang Xuefang, Tian Shuanbao
Department of Chemistry, Xinxiang Medical University, Xinxiang Henan 453003, PR China.
J Recept Signal Transduct Res. 2009;29(5):274-9. doi: 10.1080/10799890903078481.
A series of artificial 2,2'-bipyridine receptors (1, 2, 3) containing phenol group have been designed and synthesized. Their anion-binding properties are evaluated for various anions (F(-), Cl(-), Br(-), I(-), AcO(-) and H(2)PO(4)(-)) by UV-vis titration experiment in order to research the impact of different substituents on anion-recognition properties. Results indicate that the anion binding abilities can be tuned by electron push-pull properties of substituents on the phenyl ortho- or para-position of the receptors. In addition, receptor 1 is sensitive for F(-) detection without the interference of other studied anions, and receptors 2 and 3 are sensitive for H(2)PO(4)(-) detection.
一系列含有酚基的人工2,2'-联吡啶受体（1、2、3）已被设计并合成。通过紫外-可见滴定实验评估了它们对各种阴离子（F⁻、Cl⁻、Br⁻、I⁻、AcO⁻和H₂PO₄⁻）的阴离子结合性能，以研究不同取代基对阴离子识别性能的影响。结果表明，受体苯环邻位或对位取代基的电子推拉性质可调节阴离子结合能力。此外，受体1对F⁻检测敏感，不受其他研究阴离子的干扰，受体2和3对H₂PO₄⁻检测敏感。
