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[同期双侧颈淋巴结清扫术]

[Simultaneous bilateral neck dissections].

作者信息

Nishijima W, Takooda S, Usui H, Negishi T

机构信息

Department of Otolaryngology, Saitama Cancer Center.

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 1991 Aug;94(8):1104-12. doi: 10.3950/jibiinkoka.94.1104.

Abstract

From April 1985 to December 1989, 65 patients with advanced head and neck squamous cell carcinoma, underwent simultaneous bilateral neck dissection (SBND) at Saitama Cancer Center. Three and five year survival percentages were 53 and 42%, respectively. In patients without histologic involvement of cervical nodes, five year survival rate was 83%, whereas in those with nodal involvement five year survival fell to 32% (p less than 0.005). The conclusion were the following: (1) Of 38 patients diagnosed to have lymph node involvements on one side of neck before operation, 8 patients (22%) were found to have bilateral lymph node metastasis in clinicopathological study. Of 13 patients having no clinical lymph node metastasis on both sides of neck, 7 patients (54%) were found to have unilateral lymph node metastasis. Of 16 patients diagnosed to have bilateral lymph nodes involvement, 10 patients were found to have bilateral neck metastasis and 2 had unilateral neck metastasis. (2) Of 35 cases of hypopharyngeal canners, 19 cases had clinically positive lymph nodes on one side of neck. Of these 19 cases, 5 cases (26%) had histologically positive nodes on the opposite side. 14 (40%) of 35 cases had metastasis on the opposite side. In conclusion, SBND is a proper treatment for metastatic cervical cancer from a primary lesion of the head and neck, especially in hypopharyngeal cancers, because the rate of recurrence seems to be related more to the difficulty in controlling lymph node metastasis than to the failure in treatment of the primary cancer.

摘要

1985年4月至1989年12月,65例晚期头颈部鳞状细胞癌患者在埼玉癌症中心接受了双侧同期颈清扫术(SBND)。3年和5年生存率分别为53%和42%。在颈部淋巴结无组织学受累的患者中,5年生存率为83%,而在有淋巴结受累的患者中,5年生存率降至32%(p<0.005)。结论如下:(1)在术前诊断为一侧颈部淋巴结受累的38例患者中,8例(22%)在临床病理研究中发现有双侧淋巴结转移。在双侧颈部均无临床淋巴结转移的13例患者中,7例(54%)发现有单侧淋巴结转移。在诊断为双侧淋巴结受累的16例患者中,10例发现有双侧颈部转移,2例有单侧颈部转移。(2)在35例下咽癌患者中,19例临床检查发现一侧颈部淋巴结阳性。在这19例中,5例(26%)组织学检查发现对侧淋巴结阳性。35例中有14例(40%)对侧有转移。总之,SBND是治疗头颈部原发性病变所致转移性宫颈癌的一种合适方法,尤其是在下咽癌中,因为复发率似乎更多地与控制淋巴结转移的困难有关,而不是与原发癌治疗失败有关。

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