Morrison R L, Frost-Mason S K
Department of Physiology and Cell Biology, University of Kansas, Lawrence 66045-2106.
J Morphol. 1991 Aug;209(2):229-39. doi: 10.1002/jmor.1052090209.
Transmission electron microscopy (TEM) data from the ultrastructure of lizard skin iridophores (reflective dermal chromatophores) are used to illustrate the organellogenesis of small rectangular reflecting platelets, which are the color-generating components of these cells. During the development of reflecting platelets, crystals are deposited within double-membraned vesicles from electron-dense material located within the vesicles. The crystals are initially small but expanded lengthwise eventually to fill the vesicle that contains them. The inner membrane then tightly surrounds the crystal whereas the outer membrane is much more loosely associated with the inner-membrane-bound crystal. These observations allow discussion of the possible origin of the precursor double-membraned vesicles from endoplasmic reticulum (ER) and Golgi-derived vesicles. A model is proposed that incorporates our findings and other published reports to explain the origin of the precursor double-membraned vesicles via three alternative pathways.
来自蜥蜴皮肤虹彩细胞（反射性真皮色素细胞）超微结构的透射电子显微镜（TEM）数据用于说明小矩形反射血小板的细胞器发生过程，这些血小板是这些细胞产生颜色的成分。在反射血小板的发育过程中，晶体从位于囊泡内的电子致密物质沉积在双膜囊泡内。晶体最初很小，但最终沿长度方向扩展以填充包含它们的囊泡。内膜然后紧密围绕晶体，而外膜与内膜结合的晶体的关联则要松散得多。这些观察结果有助于讨论前体双膜囊泡可能源自内质网（ER）和高尔基体衍生的囊泡。提出了一个模型，该模型结合了我们的发现和其他已发表的报告，通过三种替代途径来解释前体双膜囊泡的起源。
