Bhargava M, Iyer P U, Kumar R, Ramji S, Kapani V, Bhargava S K
Department of Haematology, All India Institute of Medical Sciences, New Delhi.
J Trop Pediatr. 1991 Aug;37(4):149-52. doi: 10.1093/tropej/37.4.149.
Haemoglobin and ferritin estimations employing the micro-ELISA technique were done in 308 random selected mothers in labour and their newborns. The values of haemoglobin and serum ferritin as well as birth weight and gestation of babies born to iron depleted, and mildly and moderately anaemic mothers were no different from those of newborns of non-anaemic women. However, the values of serum ferritin per se in all these newborns were much lower than what are generally reported from the western countries. Babies born to severely anaemic women, on the other hand, showed elevated levels of haemoglobin and serum ferritin, and lower birth weights and gestation. Thus, mild to moderate iron deficiency in the mother does contribute to lower iron reserves in the foetus, if not frank iron depletion, and severe iron deficiency anaemia to lower birth weight and gestation.
采用微量酶联免疫吸附测定技术对308名随机选择的分娩母亲及其新生儿进行了血红蛋白和铁蛋白检测。铁缺乏、轻度和中度贫血母亲所生婴儿的血红蛋白和血清铁蛋白值以及出生体重和孕周与非贫血女性的新生儿无异。然而，所有这些新生儿的血清铁蛋白本身的值远低于西方国家通常报告的水平。另一方面，重度贫血女性所生婴儿的血红蛋白和血清铁蛋白水平升高，出生体重和孕周较低。因此，母亲轻度至中度缺铁即使不会导致明显的铁缺乏，也会导致胎儿铁储备降低，而严重缺铁性贫血会导致出生体重和孕周降低。
