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母体贫血时脐带血血红蛋白、铁及铁蛋白状况

Cord blood haemoglobin, iron and ferritin status in maternal anaemia.

作者信息

Agrawal R M, Tripathi A M, Agarwal K N

出版信息

Acta Paediatr Scand. 1983 Jul;72(4):545-8. doi: 10.1111/j.1651-2227.1983.tb09768.x.

Abstract

Maternal and cord blood haemoglobin, serum iron, transferrin saturation and ferritin were studied in sets of 30 anaemic (haemoglobin less than 110 g/l) and 21 nonanaemic (haemoglobin greater than or equal to 110 g/l) mothers. The cord serum iron, transferrin saturation and ferritin concentrations had significant correlation with maternal haemoglobin. The significant low levels of these parameters suggested that maternal anaemia adversely affected the iron status including iron stores of the newborns. The cord serum iron of 15.2 +/- 4.35 mumol/l and ferritin of 29.7 +/- 10.93 ng/ml seem to be effective to maintain cord haemoglobin levels. Thus, anaemic mothers with reasonably maintained ferritin and transferrin saturation levels provide sufficient iron for maintenance of cord haemoglobin, although foetal iron stores are likely to be depleted.

摘要

对30名贫血(血红蛋白低于110 g/l)和21名非贫血(血红蛋白大于或等于110 g/l)母亲的母血和脐血血红蛋白、血清铁、转铁蛋白饱和度及铁蛋白进行了研究。脐血血清铁、转铁蛋白饱和度和铁蛋白浓度与母亲血红蛋白有显著相关性。这些参数的显著低水平表明母亲贫血对包括新生儿铁储备在内的铁状态产生了不利影响。脐血血清铁15.2±4.35 μmol/l和铁蛋白29.7±10.93 ng/ml似乎对维持脐血血红蛋白水平有效。因此,铁蛋白和转铁蛋白饱和度水平合理维持的贫血母亲可为维持脐血血红蛋白提供足够的铁,尽管胎儿铁储备可能会被耗尽。

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